T follicular helper cells are essential for generating nAb during chronic-infection.

22nd January, 2018 Chronic viral infection is associated with high viral load which can lead to T cell dysfunction of  CD8 and Th1 CD4 T cells. During ...
January 22, 2018
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HIV Env immunogens elicit broad antibody responses in animal models

19th January, 2018 One goal in HIV vaccine research is the development of an antibody-based vaccine to prevent HIV acquisition. Eliciting antibodies...
January 19, 2018
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Immunological T and B cell Diversity of the Human Penis

17th January, 2018 The male genital tract is a portal of entry for many sexually transmitted infections (STIs). One of main strategies to reduce incidence of STIs...
January 17, 2018
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How does hyperglycemia lead to aggressive cancer?

15th January, 2018 Several studies have suggested that diabetes and hyperglycemia increases the risk of developing breast cancer and metastatic disease, as.....
January 15, 2018
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We need new HAB/HBV vaccine strategies for HCV/HIV infected individuals.  

12th January, 2018 Hepatitis A (HAB) and/or Hepatitis B (HBV) virus infection is common in Chronic Hepatitis C virus (HCV) and/or HIV infected individuals.
January 12, 2018
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Dengue specifc-CD8 T cell responses but not Abs provide protection against Zika

10th January, 2018 Aedes aegypti mosiquito is vector for many flaviviruses including Dengue (DENV) and Zika (ZIKV) virus. Emergence of ZIKV in the America’s has...
January 10, 2018
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Patho-physiological implication of NET in COPD patients

8th January, 2018 Neutrophils contribute to airway damage in COPD patients by releasing proteases and reactive oxygen species which can increase mucus production and...
January 8, 2018
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Phase 1 Zika vaccine trial shows promise

5th January, 2018 As of November 2017, there are 7 potential Zika vaccines consisting of one mRNA, one peptide, one recombinant viral, two DNA and two inactivated viral vaccines.Women of child-bearing age are the WHO’s main vaccination target....
January 5, 2018
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SAHGP Pilot: Southern Africans are more diverse than expected

3rd January, 2018 African populations are the most genetically diverse population and suffer the highest health burden in the world. However, genome studies of disease association rarely include...
January 3, 2018
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Whole M.tb inherently induce highly differentiated T cells compared to H56 vaccination

29th December, 2017 CD4 T cells, particularly those capable of producing IFN-γ have been shown to play an essential role in immunity...
December 29, 2017
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