Microbial dysbiosis in the gut of HIV infected patients, could trigger TLR signalling in neutrophils, increase neutrophil survival and contribute to inflammation and mucosal damage.
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Dual BCR and TCR co-expressing lymphocyte could play a role in T1D pathogenesis.
Ahmed et al., discovered this novel lymphocyte population in individuals with type 1 diabetes (T1D), and called it “dual expresser” (DE) cells because they expresses B and T cell specific genes.
M.tb resistors: M.tb uninfected or atypical IFN-𝛾-independent M.tb immune responses ?
Lu et al., demonstrate that resistors possess a distinct adaptive immune phenotype illustrated by detection of mature Ab responses and CD40L expressing (IFN-𝛾 -ve) T cells reactive to...
Course Highlight: 5th Vaccinology in Course
Very few medical interventions compete with vaccines for their cumulative impact on global health. For this reason, the Jenner institute, University of Oxford and Pirbright started vaccinology courses in Africa, where global burden of vaccine preventable...
Immunoinformatics Mexico 2019: Immunologic plasticity, defense lines.
"To maintain our homeostasis we need to constantly change and adapt to the environment," said Mariana Martínez Sánchez, during her presentation titled “Plasticity in the Immune System: From Model to Mechanisms” at Immunoinformatics 2019.
Immunoinformatics Mexico 2019: Part Two
Debora de Oliveira-Lopes explained the work-flow she utilises to identify epitopes for candidate for potential Schistosoma vaccines. She begins this process by selecting immunodominant epitopes that were identified by in-vitro antibodies (Ab) selection. She then reverse transcribes the amino-acid...
Immunoinformatics Mexico 2019: Part One
We shall share highlights of the first Latin-American Immuno-Informatics Course over the next series of articles. This course was attended with 36 participants and faculties from Africa and North & South America. To prepare regional scientists for the interdisciplinary Next Generation of Immunology,
Aiding Tuberculosis vaccine studies with the use of a mycobacterial growth inhibition assay
One of the major barriers to Tuberculosis vaccine development has been the lack of a correlate of protection or biomarker that can aid in the selection of vaccine candidates at early stages of the vaccine pipeline.
Further Support of the Emerging “Immunologic” Hypothesis in Mood and Eating Disorders
The brain and the immune system can communicate with each other in a few different ways. One way is through neural projections of the vagal and trigeminal nerves into different structures of the brain...
Immunopaedia goes to the XIII World Immune Regulation Meeting
From 6 to 9 April 2019, the XIII World Immune Regulation Meeting (WIRM) was hosted in Davos, Switzerland. The congress gathered top class worldwide researchers in basic and clinical immunology as well as eager students who presented their latest results on immune activation...