Ovarian cancer and immune evasion

In a new study published in Nature Communications, Launonen, et al., have identified and described the mechanism of how ovarian cancer hides from the body's immune system. These findings have produced novel insights for the development of new targeted therapeutics against the devastating disease.
February 18, 2022
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A new TB vaccine – is it cost-effective and efficient?

In a new study, Harris, et al., investigated the potential health impact and cost-effectiveness of the M72/AS01E vaccine in two high burden TB countries: India and South Africa
February 16, 2022
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More SARS-CoV-2 variants?

A recent paper by Foix, et al., has reported on the potential of existing strains of SARS-CoV-2, and future variants to escape the immune system's cytotoxic T cell response.
February 14, 2022
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HIV vaccine progress

In a recent paper, Ziyang, et al., have produced novel insights into and further developed an HIV vaccine through the use of a unique trimer in order to develop Tier-2 neutralizing antibodies...
February 10, 2022
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A nanoparticle based vaccine for SARS-CoV-2 neutralization and protection

In a recent study, researchers have demonstrated that the SARS-CoV-2 receptor-binding domain (RBD)-based, sortase A-conjugated nanoparticle (RBD-scNP) vaccine induces neutralizing antibodies (NAbs) in non-human primates (NHPs) against all eight variants of SARS-CoV-2.
February 7, 2022
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Predicting transplant rejection using proteoforms

In a recent study published in Science, Melani, et al., have reported on a several families of proteins in the body that may be used as a tool to predict which patients may be susceptible to rejection of a new organ transplant. This has the potential to aid clinicians in making informed decisions with regards to treatments.
February 6, 2022
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Epstein-Barr Virus found to trigger Multiple Sclerosis

For decades, researchers have suspected that patients infected with a common virus, Epstein-Barr (EVB), might be more likely to develop multiple sclerosis. Now, a team led by Harvard University researchers reports what some say is the most compelling evidence yet of a strong link between these two diseases.
February 2, 2022
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Treatment with interferon-λ confers protection from SARS-CoV-2 variants – Beta and Omicron

In a recent paper, Chong, et al., investigated the effect of IFN-λ on SARS-CoV-2 infection in mice. They found that IFN-λ conferred protection against the SARS-CoV-2 B.1.351 (Beta variant) and the newer SARS-CoV-2 B.1.1.529 (Omicron variant).
January 31, 2022
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Th17 and Multiple Sclerosis (MS)

In a recent study, Wilson, et al., have described how Th17 cell promote the onset of certain autoimmune diseases such as multiple sclerosis (MS). The researchers have discovered a mechanism used by Th17 to fulfil its function within the immune system - neutrophil extracellular traps (NETs).
January 28, 2022
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A potential end to peanut allergies?

In a recent paper, results published in The Lancet from a clinical trial has reported that through the administration of peanut oral immunotherapy in children, ages 1-3, who are extremely allergic to peanuts, safely desensitized most of them and induced remission of peanut allergy in one-fifth.
January 27, 2022
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