13th December, 2017 The female reproductive tract (FRT) has numerous physiological and immunological barriers against HIV infection. In addition to being a physical barrier..
Uncategorized
Elevated Th17 cells in “healthy” overweight children
11th December, 2017 Schindler et al. demonstrated an elevated Th17 cell function in overweight children in the absence of chronic inflammatory disease or infection....
Transphagocytic CD4+ T cells are true APC capable of inducing functional CD8 memory cells
8th December, 2017 Cruz-Adalia et al. demonstrated that tpCD4 T cells are capable of priming naïve CD8 T cells, that have a predominantly...
Potential serological test capable of distinguishing Zika from Dengue infections
6th December, 2017 Antibodies play an integral role in immunity against flavivirus infection and disease, making them ideal targets for serological diagnosis of flavivirus infections.
RTS,S/AS01E induces robust central memory responses to HBsAg but not to CSP
4th December, 2017 Moncunill et al. demonstrated that RST,S/AS01E is capable of inducing CD4+ CSP- and HBsAg-specific memory cells in vaccinated children.
CD161+CD4+ T cells depleted at the Cervix during HIV Infection
1st December, 2017 Boily-Larouche et al., observed that HIV uninfected women had higher frequencies of CD161+CD4+ T cells in the cervix compared to blood...
Regulatory T cells help prevent CMV reactivation
29th November, 2017Cytomegalovirus (CMV) infection usually results in lifelong, chronic infection. The virus remains in a latent state that eventually gets reactivated. Activation...
Asymptomatic Zika virus infection protects from re-infection
27th November, 2017Pregnant women are particularly susceptible to symptomatic Zika virus (ZIKV) infection and the virus has the ability to affect the developing fetus, resulting in a host...
PD-1-based immunotherapy affected by gut microbiome
24th November, 2017Gut microbiome dysfunction has been linked to several conditions. Researchers have now shown link between resistance to immune checkpoint inhibitors (ICI) which target...
Link between schistosomiasis and HIV susceptibility
20th November, 2017Previous studies have suggested that women who are chronically infected with schistosomiasis have increased HIV infection rates. However, prior to this current study...