17th August 2018 While improvements in screening procedures and treatments have improved colorectal cancer (CRC) patient outcomes, CRCs still account for 9-10% of all cancers worldwide. While localized cases of CRC are more easily treated, patients with ...
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How do γδ T cells control humoral immunity ?
14th August 2018 γδ T cells have also been shown to participate in induction of humoral immune responses by helping B cells. Whether γδ T cells directly interact with B cells or indirectly affect humoral immunity is not known. Additional studies have shown than γδ T cells promote B cell hypermutation by expressing ...
Can antibiotic treatment improve Rotavirus immunogenecity?
10th August 2018 Harris et al., designed a proof-of concept clinical trial that aimed to determine if mimicking some of the bacterial phenotypes observed in the observational studies is associated with improved RVV-induced immune responses.
Clade C RV144-like vaccine is immunogenic.
7th August 2018 Bekker and colleagues conducted the HVTN100 phase 1/2a clinical trial which aimed at determining the safety and immunogenicity of the Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected. adults in South Africa ...
Can B cell responses predict resolution of Lyme Disease?
3rd August 2018 Lyme disease is an infectious disease caused by Borrelia burgdorferi (Bb). Infection ...
Can profiling CD8 T cell responses from Ebola Survivors improve vaccine design?
31st July 2018 The role of CD8 T cells in protective vaccine induced responses against ebola virus is not clearly defined.
Can platelets directly kill Plasmodium sp. ?
27th July 2018 Studies have shown that platelets can bind and kill infected P.falciparum-infected RBCs (iRBC) and platelet depletion ...
Can viral Immunogenicity govern DENV epidemiological fitness ?
24th July 2018 This study demonstrated the interplay between viral replicative, immunological and epidemiological
How do tuft cells induce Type 2 Responses?
20th July 2018 A study conduted by Nadjsombati et al., aimed to determine how tuft cells are activated in the small intestines.Transcriptional profiling revealed that the ..
CD32: marker of HIV reservoir?
17th July 2018 A study published by Descours et al., in Nature last year, identified CD32a as marker of the CD4 T cell HIV reservoir. This study showed that CD32a+ CD4 T cells are enriched in HIV DNA ...