Organ specific replenishment of tissue resident macrophages

Lai et al., utilized a murine model of blood stage malaria, where mice were infected with non-lethal Plasmodium yoelii which self resolves. Blood stage malaria causes a systemic ...
December 14, 2018
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IDA Highlights: Innate signatures of HIV vaccines

The innate signatures for 4 HIV recombinant vaccine vectors (MRKAd5/HIV, ALVAC ,MVA and Vesicular Stomatitis Virus (VSV) and their respective adjuvants have been evaluated or are under...
December 11, 2018
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IDA Highlights: TB vaccines

The future vaccination against TB will likely be based on heterologous prime-boost strategies. These strategies consist of subsequent vaccinations with new vaccine candidates following primary BCG vaccination ...
December 7, 2018
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IDA Highlights: HIV Immunity

The lymph nodes has shown to be one compartment with highest rates of HIV replication and yet has a restrictive trafficking of cytotoxic CD8 T-cells into the tissues (Michael Betts). However ...
December 4, 2018
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What’s behind Eosinophilic Esophagitis?

30th November 2018 Eosinophilic esophagitis (EoE) is a rare, chronic, food-driven inflammatory disease of the esophagus. Clinical presentation varies through different ages and may include feeding...
November 30, 2018
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IDA Highlights: Malaria

28th November 2018 Antibodies induced by natural infection confer protective immunity in individuals from Malaria endemic regions. Efforts to induce potent vaccine...
November 28, 2018
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IDA Highlight: TB is a complex disease

22nd November 2018 90% of people exposed to  Mycobacterium tuberculosis (M.tb) clear infection or contain the infection (termed as latency), however there is a percentage that progress to active disease.
November 22, 2018
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IDA Highlights: Immune responses at mucosal sites

20th November 2018 The mucosal sites are usually the first entry points of HIV, hence this site is one of the key target areas for anti-HIV immune interventions. To emphasize this point Thomas J Hope ...
November 20, 2018
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Intestinal helminth co-infection promotes control against lung migrating parasites

9th November 2018 Filbey et al., aimed to determine how chronic Heligmosomoides polygyrus (Hp) gastrointestinal infection can influence systemic and localised immunity against other helminth infections.
November 9, 2018
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Characterisation of porcine conventional DC subsets

6th November 2018 DEC205 plays a very important role in antigen presentation and cross-presentation by cDCs. This has led to the study of antigen-targeting of DEC205 for vaccination.
November 6, 2018
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