In response to environmental changes and nutrient starvation, cells are known to undergo extreme alterations. This includes switching from one type to another (“differentiation”) and changes in metabolic pathways (“metabolic switching”).
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Can intravenous-BCG prevent M.tb infection ?
In this article, we highlight a recently published article by Darrah et al., which aimed to determine how dose and route of BCG vaccination influence the generation of systemic and tissue-resident immunity, as well as “protect” against TB. In their study, they vaccinated non-human primates...
How does group A Streptococcus evade immunity?
Wierzbicki et al., utilised Biomimetic Virulomics a nanotechnology-enabled affinity enrichment coupled with multiplexed quantitative proteomics platform to enrich red blood cell (RBC)-specific effector proteins secreted by GAS.
TB biomarker based on anti-Ag85B and 4 inflammatory molecules.
We report findings from a recently published article “A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough”(Ahmed et al., 2019).Ahmed et al., “hypothesized that a blood protein-based...
Immuno-Jaipur Highlight: Primary immunodeficiencies
In our final article about the proceedings of the Immuno-Jaipur course, we shall highlight talks given by faculty about their research on PIDS. Children with PIDs are often misdiagnosed for cancers due to have.
Immuno-Jaipur Highlight: Clinical viral immunity
This article highlights talks about viral immunity. Prof Gray presented his research on the impact of HIV on placental and fetal immunity, while Dr Groom presented on the importance of microscopic imaging in understanding viral immunity.
Immuno-Jaipur Highlight: MHC and Transplantation Immunology
The theme of the 5th and last day of Immuno-Jaipur was Clinical Immunology, which included talks from researchers that conduct translational research. In this article we shall highlight talks by Dr Narinder Mehra and Rajalingum Raja, who presented talks on Human Leukocyte Antigen (HLA) system immunology.
Immuno-Jaipur Highlight : Part 2 of Day 4
Day 4 of Immuno-Jaipur included talks by Oliver Boyer and Hannes Stockinger. Prof. Olivier Boyer lecture highlighted the origin and perspectives of CAR-T cells for treatment of cancer patients. He briefed the design of chimeric antigen receptor construct which consist of the extracellular...
Immuno-Jaipur Highlight : Day 4
Day 4 of the Immuno-Jaipur included talks from renowned Professors Shubhada Chiplunka, Sunil Arora, Hannes Stockinger, Abul Abbas and Oliver Boyer. In think article we shall highlights information relayed by Profs Chuplunka, Arora and Abbas. Prof. Shubhada Chiplunkar, ACTREC-Tata Memorial Centre, addressed the audience on the...
Immuno-Jaipur Highlight: Part 2 of Day 3
In addition to talks by Prof Abbas, Day 3 of Immuno-Jaipur included talks on autoimmunity and chronic inflammation. Prof. Bernhard Fleisher gave a talk on autoimmunity in the central nervous system where he discussed various autoimmune diseases such as Myasthenia Gravis, Encephalitis, Multiple sclerosis. Myasthenia gravis is an autoimmune disease...