A recent study by Allen, et al., reported a positive genetic correlation between IPF and severe COVID-19 risk. However, it must be noted that some of the IPF-related pathways may have a contrasting effect on severe COVID-19 risk. An interesting paper where limitations have been noted.
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Can fat help us combat infection?
In a new study from Nature Communications, Mistry, et al., have reported on how our immune cells use Free Fatty-acid (FFA) transport to fight infection. These insights could help develop new methods of treating bacterial infections.
Antibody profile in response to SARS-CoV-2 – serological profile and specificity of maternal and neonatal cord blood
In a recent study, researchers investigated the antibody profile of maternal serum and neonatal cord blood antibody responses to SARS-CoV-2 virus exposure in mothers.
Germline mutations in innate immunity associated with the risk for breast cancer: case of C-reactive protein
A study by Su et al has demonstrated that using a Mendelian randomization approach reduce environmental bias on the causal relationship between genetically elevated CRP levels and postmenopausal breast cancer risk.
New Insights into the diagnosis, prognosis and monitoring of Multiple Myeloma: What’s the role of the Heavy/Light Chain Assay?
In a recent review, Rios-Tamayo, et al., summarize the current basic laboratory testing in multiple myeloma patients and propose a new algorithm to manage and follow up the MP based on the heavy/light chain assay.
Antiretroviral therapy influences tumour development in patients with HIV
In a new study, Saluzzo, et al., has reported that the time of starting antiretroviral therapy may influence tumour development. A novel finding as the mechanism underlying the pathophysiology of chronic tissue-related...
Promotion of protective anti-tumour CD8+ T cell immunity – a new treatment for tumours
In a recent study by researchers at MIT, Duong, et al., have identified a potential approach to indirectly activate T cells, through the recruitment of a helper immune cells i.e. dendritic cells. An interesting new approach to immunotherapy.
Alzheimer’s Disease – a potential vaccine?
In a promising new study, researchers from the University of Leicester have developed a new approach to potentially treating and vaccinating against Alzheimer’s disease. An potentially major finding that may have immense implications. Could this be what the world has been waiting for...
Immune system evasion – the HIV-infected cell
In a new study published in PLOS Pathogens, researchers have demonstrated how specific features on the surface of HIV-infected cells play a key role in immune system evasion. A significant and novel finding...
Improving existing malaria vaccines – new insights
In a new study, researchers from the University of Copenhagen and their collaborators, have reported on new insights into acquired adaptive immunity towards malaria following infection and vaccination. An interesting comparison...