Roediger, et al., suggested that the role of T cells, particularly due to their implication in the TH2 phenotype, in Inflammatory skin disease (ISD) could be a therapeutic avenue which can extend to cutaneous lymphoma disease (CTCL)...
Uncategorized
B-cell immunity following SARS-COV-2 mRNA vaccination – 6 months on…
In a recent paper by Markewitz, et al., the researchers aimed to investigate and determine the levels of anti-SARS-CoV-2 antibodies in individuals who have been vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose...
A potential mRNA vaccine for SARS-CoV-2 Omicron variant
In a recent study, Wu, et al., aimed to develop a messenger ribonucleic acid (mRNA) vaccine using the SARS-CoV-2 Omicron variant sequence as a target. The aim was to develop a vaccine capable of generating nAbs in multiple animal models against the Omicron variant...
More than a gut feeling: The implication of gut microbiota in the pathology of Alzheimer’s Disease
A recent study by Verhaar et al, investigated associations among patients with Alzheimer's' disease pathology and their gut microbiota. This study demonstrates that the gut microbiome composition is linked to biomarkers of AD pathology...
MAIT cells – a new target for future immunotherapies and vaccines
In a recent study, researchers have demonstrated that mucosal-associated invariant T (MAIT) cells, a form of immune cells, play several complex roles during diseased and healthy conditions. These MAIT cells may be used as targets for immunotherapies and vaccines.
Immune memory in the intestine: new insights into “innate memory”
In a recent paper, Serafinain, et al., have made us of an intestinal infection model to discover that group 3 innate lymphoid cells (cells of the innate immune system) may also develop an innate form of immunological memory...
A new tool fight SARS-CoV-2: an ACE2-blocking antibody
In a new study, Du, et al., have identified a neutralising monoclonal antibody in humans, 87G7, against SARS-CoV-2 which has shown widespread neutralisation and immunisation efficacy against SARS-CoV-2 VOCs...
Novel HIV-1 variant found in Netherlands: the implications
In recent study published in Science, Wymant, et al., reported the presence of a subtype-B variant of HIV-1 with high virulence that has been spreading through the Netherlands during recent times. Does this highlight the importance of monitoring viral variants?
Understanding the immune system and COVID-19: New insights
Researchers today are still trying to understand how the immune system's natural killer (NK) cells identify SARS-CoV-2 infected cells. In a recent paper, Hammer, et al., have reported that NK cells respond to a certain peptide on the surface of infected cells...
Ovarian cancer and immune evasion
In a new study published in Nature Communications, Launonen, et al., have identified and described the mechanism of how ovarian cancer hides from the body's immune system. These findings have produced novel insights for the development of new targeted therapeutics against the devastating disease.