In a recent paper, researchers were able to show that the development of LRRC15+ myofibroblasts during the process of tumorigenesis is supported by TGFβ signalling in dermatopontin positive (DPT+) universal fibroblasts...
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The opportunity to boost antiretroviral therapy interventions through maternal vaccination
In a recent paper, researchers proposed the concept of maternal vaccination to help boost the effectiveness of ART to reduce mother-to-child transmission of HIV...
Rebound to COVID-19 – not from impaired immunity
In a recent paper, researchers have found that rebounding to COVID-19 is not likely to be caused by an inefficient or impaired immune response, Looking at 8 patients who have taken nirmatrelvir/ritonavir...
The humoral response as a marker in patients with chronic obstructive pulmonary disease
In a new study, researchers aimed to determine the markers of inflammation within different categories of patients with COPD, that is, those with rapid, slow or no lung functional decline...
How to boost immunotherapies against B-cell leukemia
In a new study, Witkowski, et al., have identified novel regulators by using a surface CD19-guided whole-genome CRISPR-Cas9 screening platform to ensure the complete elimination of malignant cells by certain immunotherapies...
SARS-CoV-2 can infect adipose tissue
A recent study had researchers show that SARS-CoV-2 is capable of infecting human fat tissue. In this study they looked at fat tissue biopsied from patients undergoing bariatric and cardiac surgeries...
Lack of sleep and your immune system
In a recent paper, researchers have described how a consistent lack of sleep can have significant negative effects on your immune system, with harmful affects observed in immune cells, leading to inflammatory disorders and cardiovascular disease...
What effect does anti PD-1 therapy have on responses to the influenza vaccine?
In a new study, researchers sought to find what effect anti-PD-1 immunotherapies have on the Tfh–B cell axis. To study this, they had a look at the immune responses induced by the influenza vaccine...
Vaccine-associated enhanced respiratory disease in hamsters vaccinated against COVID-19
In this study, Ebenig and colleagues were able to come up with a detailed description of what they believe to be the immune-cell mediated mechanisms responsible for inducing Vaccine-associated enhanced respiratory disease (VAERD)...
Increased activity of Neutrophil Elastase in sera of SLE patients during the COVID-19 pandemic
In a new study, Knopf and colleagues now assessed the serological changes in the serum of patients with SLE with regards to NET formation in samples taken before and during the pandemic...