In a promising new study, researchers from the University of Leicester have developed a new approach to potentially treating and vaccinating against Alzheimer’s disease. An potentially major finding that may have immense implications. Could this be what the world has been waiting for...
2021
Immune system evasion – the HIV-infected cell
In a new study published in PLOS Pathogens, researchers have demonstrated how specific features on the surface of HIV-infected cells play a key role in immune system evasion. A significant and novel finding...
Improving existing malaria vaccines – new insights
In a new study, researchers from the University of Copenhagen and their collaborators, have reported on new insights into acquired adaptive immunity towards malaria following infection and vaccination. An interesting comparison...
Detection of autoantibodies in patients with multisystem inflammatory syndrome in children (MIS-C)
In a recent study, researchers aimed to characterise the presence of autoantibodies against autoantigens associated with known autoimmune diseases...
Immunotherapy – new insights into how CD8+ T cells become unresponsive to treatment
In a recent paper, Horten, et al., have revealed potential causes for T cells exhaustion and how this subset may become non-responsive to immune checkpoint blockade (ICB).
Predicting response to immunotherapy in patients with clear cell renal cell carcinoma (ccRCC)
Recently, researchers have identified patterns within tumours that will help with predicting if patients with kidney cancer will respond to immunotherapy.
Pregnancy and its influence on the immune response to SARS-CoV-2
A recently published focus article has highlighted two interesting studies which investigated the response of pregnant women to natural infections and COVID-19 vaccines. The results are interesting...
Toxoplasma gondii-Induced Neutrophil Extracellular Traps Activate Neutrophils and promote T cell recruitment
Researchers have now determined the activation status of human neutrophils from patients with acute and chronic infections of T. gondii using flow cytometry.
Neutrophils as potential early indicators of tuberculosis severity
Researchers have made use of flow cytometry to monitor frequencies, phenotype and function of stimulated neutrophils from HIV-negative TB patients...
Microbial fitness and IgA – a balancing act for the intestinal flora
Researchers have recently shown in a murine model that IgA antibodies regulate and modulate, at several levels, the activity of non-pathogenic bacteria...