Researchers from California have identified molecular biomarkers, pathways and immune cell dynamics associated with sepsis that can be potentially targeted in order to prevent death from and develop new treatments for sepsis.
September 2021
Identification of D6R and C5aR2 as key molecules with the potential to combat inflammatory diseases
Researchers have identified key molecules within the immune system that have the potential, through their use, to combat inflammation implicated in chronic diseases including COVID-19, cancers and...
Microglial cells – immune cells of the CNS breaking down harmful proteins in the brain
Researchers from the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE), and the Institut François Jacob in France have identified a mechanism describing α-syn accumulation and microglial degradation.
A new cell type contributing to inflammatory skin diseases
In an interesting discovery, an international team of researchers have identified and described a new cell type in human skin that contributes to inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis (PSO).
How does vitamin A enter our intestinal immune cells and what are the implications?
Researchers from the University of Texas Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines. Implications - improving vaccine efficacy to the potential treatment of digestive diseases.
Neutrophilic aid – extracellular traps to enhance macrophage directed bacterial killing
Recently, researchers have identified a novel antibacterial mechanism, potentially paving the way for new therapeutics to combat Staphylococcus aureus infection and other bacterial infection.
A new tool for predicting COVID-19 severity and prognosis
Through the investigation of novel biological features explaining COVID-19 severity and prognosis (death and disease progression), researchers have developed a novel predictive tool which they have made publicly available...
Ad26.CoV2.S vaccine significantly boosts pre-existing SARS-CoV-2 specific antibodies but not CD4 T cell immune responses
8 September 2021 In a recent Pre-print, Keeton et al., examined the effect of prior infection with ancestral (D614G) or Beta variants on Ad26.COV2.S immunogenicity approximately 28 days...
A potential new biomarker for Preeclampsia
3 September 2021 Preeclampsia (PE) is a devastating disorder which effects more than 3-5% of pregnancies worldwide and remains to be one of the leading causes of global maternal and perinatal mortality and morbidity. Having previously observed aberrant expression of human leukocyte antigen (HLA)-DR molecules in the syncytiotrophoblast of a subset of women with PE...