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Immunology News 2020 October

October 2020

SAIS/Immunopaedia Webinar: Immunothrombosis & COVID-19

We highlight SAIS/Immunopaedia COVID-19 Webinar featuring talks by haematopathologists Dr Susan Louw and A/Prof Jessica Olpie on immunothrombosis & COVID-19. Dr Susan Louw began her talk...
October 7, 2020
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Safety and immunogenicity of the SARS-CoV-2 mRNA-1273 vaccine candidate in older age.

A follow-up article published in NEJM showed that the mRNA vaccine, mRNA-1273, was safe and immunogenic in older vaccine volunteers (56-70 years). The vaccine has also been shown to be safe and immunogenic in younger people.
October 6, 2020
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Genetically modified Lactococcus lactis- A potential microbial therapeutic for acute colitis?

Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is a complex inflammatory disorder of the gastrointestinal tract. The incidence of IBD is on the rise worldwide and possible triggers of the disease include an inflammatory response ...
October 5, 2020
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IUIS Webinar: Impairment of the immunological and neurological synapses by respiratory viruses

The last IUIS COVID-19 webinar featured a talk by Alexi Kalergis: Impairment of the immunological and neurological synapses by respiratory viruses and the implications for the design of vaccines.
October 2, 2020
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  • 2023
    • September
      • Test News
    • August
      • Evaluating a Peptide-Based T-Cell Activating COVID-19 vaccine - Insights from a Phase I/II Trial
      • Parkinson's disease – new insights into immune cell landscape
      • Using a virus to treat Pancreatic Cancer
      • More robust immune systems in children from rural areas
      • Mapping macrophage diversity in liver diseases
      • T cells and type 1 diabetes prevention
      • The potential of T cell activation markers for TB diagnostic development
    • July
      • The landscape of human cornea – immune cells
      • Immunoregulation in the brain – new insights
      • Mitchondrial disorder linked to a weaker immune response
      • Allergen sensitization – insights into atopic dermatitis and other skin disorders
      • Key discovery in our battle against HIV
      • MS, inflammation and the brain – new insights
      • How melanoma evades the immune system
      • B cells and PCOS
      • Single-cell RNA sequencing – new insights into cancer
      • New insights into inflammation
      • How metabolic rewiring influences macrophage function
      • Early loss of a parent may impact our immune systems
      • Lupus and the microbiome – the flare
    • June
      • Anti-tumour T-cell activation from B-cells
      • Making cancer immunotherapy safer
      • Genetics and allergies
      • Placental protection of the fetus – new insights
      • Respiratory Syncytial Virus (RSV) infection – the role of T cells
      • The immune system during old age
      • Skin aging – IL-17 a role player
      • Harmful blood in the brain – immune insights
      • Autoantibodies in Systemic Autoimmune Diseases
      • Stress mediated stirring up of the immune system
      • New insights - drug resistance malaria
    • May
      • Decoding HIV – insights from an animal model
      • Smallpox vaccine for mpox?
      • Single cell profiling at the maternal–fetal interface - insights
      • A skin patch for peanut allergy
      • A positive sign for prostate cancer treatment
      • Inflammatory bowel disease – mapping the immune system of the gut
      • TB and HIV – an enhanced antibody response
      • Modelling the brain – new insights
      • How some individuals with immunodeficiency defend themselves against infection
      • Using gamma T cells to fight TNBC
      • PSGL-1 regulates CD8+ T Cell Exhaustion
    • April
      • Clear cell renal cell carcinoma – new “spatial,” insights
      • Chronic transplant rejection – new insights
      • Possible new treatment for rheumatoid arthritis
      • Using lab grown organs to test vaccines
      • Immunity in centenarians – keys to life?
      • Improving pancreatic cancer therapy - insights
      • The early stages of HIV infection – new insights
      • Phosphatidylserine-positive extracellular vesicles - boosting effector CD8+ T cell responses
      • Regulatory T cells – new insights
      • How neutrophils can be used to fight cancer
      • New insights into mechanisms of HIV infection
    • March
      • Enhancing the immune system to fight TB infection
      • COVID-19 and HIV – how antibody responses are affected
      • The immune system and liver disease – new insights
      • The immune system – new insights
      • Is trained immunity impacted by revaccination or BCG dose?
      • Inflammation in soft gums - insights
      • The role of T cells in Alzheimer's disease – novel insights
      • COVID-19 – creating a vaccine that can change with the virus
      • Eliminating metastatic breast cancer in mice – immunotherapy insights
      • How immune cells fight chronic infection or disease - new insights
      • Specific B cell targeting to treat lupus
      • Why prematurely born babies are more susceptible to infection
      • What drives allergic asthma? New insights
    • February
      • First COVID-19 vaccination may affect booster shot efficacy
      • Defining more roles for Natural Killer cells
      • A potential cure for HIV may exist in stem cell transplantation – however…
      • Priming the immune response with ginger
      • T-cell protection against pneumococcal disease
      • Is salt bad for you? Starving immune regulators of energy
      • Blocking SARS-CoV-2 infection – new insights
      • T cell exhaustion- new insights
      • Do your genetics make you more susceptible to infections?
      • New TB drug regimen may not work against TB meningitis
    • January
      • Epstein-Barr virus – novel insights into the immune response to the virus
      • Novel insights into the treatment of lupus
      • COVID-19 and the innate immune system – long term effects
      • Immune response diversity driven by B cells
      • Understanding gut inflammation using caterpillars
      • Vaccines and respiratory viruses
      • Insights into the mechanism lung cancers use to evade the immune system
      • Newly discovered IFN-γ role in Metabolic reprogramming to support Tumor Evasion
      • A vaccine for brain cancer?
      • COVID-19 vaccination may offer cancer protection
      • Novel therapy to reduce immune rejection of transplant cells
  • 2022
    • December
      • Why we lose our smell – COVID-19
      • Insights into the regulation of inflammation
      • Blood clotting – insights into sepsis
      • Respiratory infections – common (in) cold (temperatures)
      • Your gut microbiome and white blood cells
      • Leukemia linked T cells may drive autoimmune diseases
      • Predicting patient responses to COVID-19 immunotherapies
    • November
      • Neurological effects of COVID-19
      • HIV and its mechanisms of drug evasion
      • Axon regeneration in the adult nervous system – immune modulation
      • Atypical B cells as biomarkers of renal complication in lupus patients
      • Improved cancer treatment response in those with COVID vaccination
      • Tumor associated macrophages: the future targets for anti-melanoma immunotherapy ?
      • Novel insights – regulating skin inflammation
      • Vimentin and its role in COVID-19 infection
      • How the brain slows us down when we are sick
      • Improving vaccine immunity against fungal pneumonia
    • October
      • Time of day for COVID-19 vaccination does not matter
      • Non-invasive tumour immune cell monitoring
      • Infection in the brain - defenses and consequences
      • What determines COVID-19 disease persistence and severity?
      • Novel treatment approach for asthma without negative immune system effects
      • Development and use of cellular behavioural landscapes to describe inflammatory states
      • The interplay between LRRC15+ myofibroblasts and anti-tumour immunity
      • The opportunity to boost antiretroviral therapy interventions through maternal vaccination
      • Rebound to COVID-19 – not from impaired immunity
      • The humoral response as a marker in patients with chronic obstructive pulmonary disease
      • How to boost immunotherapies against B-cell leukemia
      • SARS-CoV-2 can infect adipose tissue
    • September
      • Lack of sleep and your immune system
      • What effect does anti PD-1 therapy have on responses to the influenza vaccine?
      • Vaccine-associated enhanced respiratory disease in hamsters vaccinated against COVID-19
      • Increased activity of Neutrophil Elastase in sera of SLE patients during the COVID-19 pandemic
      • Inhibiting Mycobacterium tuberculosis infection
      • SARS-CoV-2 infection following vaccination – more robust immunity
      • Novel protein linked to rheumatoid arthritis pathogenesis
      • Using viruses to fight cancer
      • Antibodies from cows may provide protection from Mycobacterium avium subsp. paratuberculosis
      • A ‘side-ways’ mechanism of detection in CD1a and γδ T cell receptor interactions
      • Neutrophils as biomarkers for COVID-19 and recovery
      • What does HIV infection have to do with T follicular regulatory cells (TFRs)?
    • August
      • What role do CD137L and CD4 T-cells have in B-cell lymphoma immuno-surveillance?
      • Blocking of an important coronavirus enzyme with natural compounds
      • Helminths and Vaccine responses
      • A map of the immune system
      • CD8 T-cell mediated vaccine protection against SARS-CoV-2
      • The emergence of inflammatory monocytes as the leukemia anteroom.
      • New insights into the interferon response to SARS-CoV-2
      • Distinct antibody responses as biomarkers to monitor cancer immunotherapies
      • Promising new insights: the immune response following a stroke
      • IL-25 blockade as a therapeutic strategy for asthma
      • Using bacteria to fight cancer
      • Unique genes: the innate immune response and tuberculosis
      • SARS-CoV-2 Omicron variant in hamsters is not as deadly as we think
    • July
      • Nasal spray immunisation: potential use against HIV and SARS-CoV-2 shown in an animal models
      • Cancer, collagen the microbiome and immunity – a link!
      • COVID-19 and the brain - new insights
      • Can reprogramming CD8 T-cells contribute to a cure for a HIV?
      • An inflammatory pathway linked to autoimmune diseases
      • Developing new tools to combat COVID-19
      • SARS-CoV-2 omicron variant hardly evade neutralization by S309
      • Hair growth and our immune system
      • SARS-CoV-2 – a weakness?
      • The immune system and obesity
      • Adaptations of tissue-resident memory T cells
      • Using lipid nanoparticles for cancer treatment
      • A vaccine with a dual threat to cancer
    • June
      • Can BCG vaccination reduce mortality and morbidity from COVID-19?
      • A potential new vaccine for rabies
      • Does cancer immunoediting occur in humans?
      • What happens to your cilia during SARS-CoV-2 infection?
      • T cell lineage fate is driven by CD4 and CD8 co-receptor gene loci
      • Novel insights: immunotherapy responses in lung cancer
      • Comparing four COVID-19 vaccines
      • Does the timing of granuloma formation affect TB control?
      • ATLAS – describing SARS-CoV-2 variant T-cell responses
      • Human M1 macrophages champion the control of TB disease
    • May
      • Cannabidiol - a potential tool for fighting SARS-CoV-2
      • Improving Chagas disease diagnosis and treatment
      • Bifonazole - a potential treatment for SARS-CoV-2 infection
      • Immunodiagnostic of onchocerciasis: do we have the right tool to end the game?
      • Stopping inflammation in its tracks
      • T cells and melanomas - a potential predictive tool
      • COVID-19 mortality and genetic predisposition
      • Novel vaccines induce neutralising antibodies against Epstein-Barr virus in mice
      • SARS-CoV-2 and partial resistance to remdesivir
      • Enhancing the immune response: skin bacteria and the smallpox vaccination
      • Leaky gut in COVID-19 and its impact on Neutrophil Extracellular Trap formation
    • April
      • Where is single cell genomics taking the field of Immunology?
      • TB diagnosis in children: metabolite biomarkers
      • Atopic dermatitis and the skin microbiome
      • Improving treatments for autoimmune diseases
      • Developing monoclonal antibodies against SARS-CoV-2
      • TB treatment with diabetes comorbidity: new insights
      • SARS-CoV-2 and T-cell escape
      • B cell signalling deficiencies – new insights into treatments
      • SARS-CoV-2 and mucosal immunity
      • The role of the PD-1 blockade in Mycobacterium tuberculosis infection
      • Sugar and autoimmune diseases: what are the risks?
    • March
      • B-cell immunity against SARS-CoV-2 in unexposed individuals
      • Enhanced production of effective and personalised vaccines for cancer
      • COVID-19: antigen-specific T cell response and immuno-metabolomic signatures
      • Biomarkers to identify Mycobacterium tuberculosis-infection: finding the needle in a haystack
      • T cells and skin disease
      • B-cell immunity following SARS-COV-2 mRNA vaccination – 6 months on…
      • A potential mRNA vaccine for SARS-CoV-2 Omicron variant
      • More than a gut feeling: The implication of gut microbiota in the pathology of Alzheimer’s Disease
      • MAIT cells – a new target for future immunotherapies and vaccines
      • Immune memory in the intestine: new insights into "innate memory"
    • February
      • A new tool fight SARS-CoV-2: an ACE2-blocking antibody
      • Novel HIV-1 variant found in Netherlands: the implications
      • Understanding the immune system and COVID-19: New insights
      • Ovarian cancer and immune evasion
      • A new TB vaccine – is it cost-effective and efficient?
      • More SARS-CoV-2 variants?
      • HIV vaccine progress
      • A nanoparticle based vaccine for SARS-CoV-2 neutralization and protection
      • Predicting transplant rejection using proteoforms
      • Epstein-Barr Virus found to trigger Multiple Sclerosis
    • January
      • Treatment with interferon-λ confers protection from SARS-CoV-2 variants - Beta and Omicron
      • Th17 and Multiple Sclerosis (MS)
      • A potential end to peanut allergies?
      • Why is SARS-CoV-2 Omicron less severe than Delta?
      • A new target for TB treatment with great potential
      • Formation of tertiary lymphoid tissue: fighting chronic inflammation
      • Our natural defence to skin cancer – new insights
      • Can we use cannabinoids to block SARS-CoV-2 viral entry?
      • Toothpaste - a trigger for gut inflammation
      • How do immune cells invade tissue?
      • T-cell response to SARS-CoV-2 Omicron
  • 2021
    • December
      • B cell lymphomas and the role of TET enzymes
      • Changes in SARS-CoV-2 Omicron variant spike protein
      • Resistance to key antimalarial drug?
      • COVID-19 and idiopathic pulmonary fibrosis (IPF)
      • Can fat help us combat infection?
      • Antibody profile in response to SARS-CoV-2 – serological profile and specificity of maternal and neonatal cord blood
      • Germline mutations in innate immunity associated with the risk for breast cancer: case of C-reactive protein
      • New Insights into the diagnosis, prognosis and monitoring of Multiple Myeloma: What’s the role of the Heavy/Light Chain Assay?
    • November
      • Antiretroviral therapy influences tumour development in patients with HIV
      • Promotion of protective anti-tumour CD8+ T cell immunity – a new treatment for tumours
      • Alzheimer’s Disease – a potential vaccine?
      • Immune system evasion – the HIV-infected cell
      • Improving existing malaria vaccines – new insights
      • Detection of autoantibodies in patients with multisystem inflammatory syndrome in children (MIS-C)
      • Immunotherapy – new insights into how CD8+ T cells become unresponsive to treatment
      • Predicting response to immunotherapy in patients with clear cell renal cell carcinoma (ccRCC)
      • Pregnancy and its influence on the immune response to SARS-CoV-2
    • October
      • Toxoplasma gondii-Induced Neutrophil Extracellular Traps Activate Neutrophils and promote T cell recruitment
      • Neutrophils as potential early indicators of tuberculosis severity
      • Microbial fitness and IgA - a balancing act for the intestinal flora
      • Malaria Vaccine Breakthrough: Shaking or Stirring the Field?
      • A novel immunogene CD47-targeting therapy inhibiting tumour growth
      • A novel inhibitor of dengue virus
      • Variations in leukocytes - three months following mild COVID-19 infection
      • Insights into the development of the blood and immune systems in prenatal bone marrow
    • September
      • New hope – a potential new treatment for sepsis
      • Identification of D6R and C5aR2 as key molecules with the potential to combat inflammatory diseases
      • Microglial cells – immune cells of the CNS breaking down harmful proteins in the brain
      • A new cell type contributing to inflammatory skin diseases
      • How does vitamin A enter our intestinal immune cells and what are the implications?
      • Neutrophilic aid – extracellular traps to enhance macrophage directed bacterial killing
      • A new tool for predicting COVID-19 severity and prognosis
      • Ad26.CoV2.S vaccine significantly boosts pre-existing SARS-CoV-2 specific antibodies but not CD4 T cell immune responses
      • A potential new biomarker for Preeclampsia
    • August
      • Reprogramming the Tumour Microenvironment – Improving Cancer Survival
      • Does B.1.351 SARS-CoV-2 variant escape T cell immune responses?
      • Neutrophil dominance leads to protection from P. falciparum blood-stage merozoites
      • A novel pathway of immune and host cell evasion by Mycobacterium tuberculosis
      • Pre-clinical evaluation of a vaccine that induces both SARS-Cov-2 and yellow fever virus immunity.
      • Can neutrophils adopt antigen-presenting cell functions, and if so how?
      • IUIS Webinar: HIV prevention- antibodies and vaccine development (part 2)
      • IUIS Webinar: HIV prevention- antibodies and vaccine development (part 1)
      • Potent neutralising antibodies against SARS-CoV-2 variants of concern.
    • July
      • World Hepatitis Day: proof of concept HCV nanoparticle vaccine
      • Immunogenicity of heterologous SARS-CoV-2 vector vaccine prime-mRNA vaccine boost vaccination strategy
      • Global Immunotalks Highlight: Immune responses after dengue virus infection: friend or foe?
      • What does HLA-DR expression on CD4 T cells indicate?
      • IUIS-Immunopaedia-Frontiers Webinar: Immunopathology of COVID 19 lessons from pregnancy and from ageing
      • Could infection with other viruses provide protection from SARS-CoV-2?
      • Microbes prime foetal immune cells during early human development
      • The role of emergent food allergies in rethinking vaccine strategies
      • How Sickle-trait hemoglobin protects against severe Plasmodium falciparum malaria
    • June
      • HIV-1 and TB coinfection skews the SARS-CoV-2 T cell response
      • WNT7A: The new marker for resting T cells
      • Does serial administration of HIV-specific VRC01 bnAbs prevent HIV acquisition?
      • An update on the Shock and kill HIV cure strategy
      • IUIS-Immunopaedia-Frontiers Webinar: Clinical representation of hyperinflammation
      • IUIS-Immunopaedia-Frontiers webinar: In-depth characterisation of immune cells in Ebola virus.
      • BCG reduces all-cause infectious diseases in the first 6 weeks of life in infants!
      • IUIS-Immunopaedia-Frontiers webinar: Getting to the “bottom” of arthritis
      • Immuno-Colombia: Overview of immunotherapy
      • Immuno-Colombia: Therapeutic cancer vaccines
    • May
      • Immuno-Colombia: Tumour infiltrating lymphocyte therapy (Part 2)
      • Immuno-Colombia: Tumour infiltrating lymphocyte therapy (Part 1)
      • Immuno-Colombia: MDSCs promote tumour growth and escape
      • Immuno-Colombia: Anti-cytokine therapies (Part 2)
      • Immuno-Colombia: Anti-cytokine therapies (Part 1)
      • Immuno-Colombia: Checkpoint Blockade-based Therapies (Part 2)
      • Immuno-Colombia: Checkpoint Blockade-based Therapies (Part 1)
      • Exploring characteristics of COVID-19 to guide public health policies & therapeutic interventions.
      • C5a-C5aR1 axis plays a role in cobra venom immunopathology.
      • Antibody response to vaccination post-COVID-19 infection
    • April
      • Aged Neutrophils support tumor metastasis
      • P.falciparum secretes extracellular vesicles with functional 20S proteasomes to prime RBCs for parasite invasion
      • Pregnant women show elevated levels of anti-inflammatory glycosylation patterns of IgG antibodies
      • First report on Effectiveness of HPV Vaccination in LMICs - Rwanda and Bhutan
      • Does ACE2 expression & cytotoxic lymphocyte levels indicate a risk factor for COVID-19?
      • Immunopathogenesis of Autoimmune Hepatitis
      • B1.351 (501Y.V2) induces cross-reactive Ab responses to other SARS-CoV-2 variants.
      • IUIS-Immunopaedia-Frontiers Webinar on Immunology taught by P. falciparum
      • Is tumour circulating DNA a better tool for cancer diagnostic and prognostic than immunological biomarkers?
    • March
      • HPV & HIV infection are associated with high levels of activated CD4 T cells in the cervix uteri
      • Predicting tissue graft outcomes using immune markers
      • JoAnne Flynn: BCG IV vaccination induces sterilising M.tb immunity.
      • Flynn Webinar: What immune cells play a role in protection against M.tb re-infection?
      • Flynn Webinar: Immune features associated natural infection
      • BCG vaccination reduces infection in the elderly
      • Exploratory study investigates the relationship between recent vaccinations and SARS-CoV-2 infection rates.
      • Statins: improved survival rates and reduced mortality rate in COVID-19 patients.
      • Myeloid-derived suppressor cells: drivers of severe COVID-19 disease?
      • Webinar on harnessing innate immunity from cancer therapy to COVID-19
    • February
      • Uterine NK cell differentiation during the menstrual cycle and pregnancy.
      • Global ImmunoTalk on dissecting the interaction of parasites with the immune system
      • Researchers may have found a way to "cure" cat allergies?
      • The antibody response to SARS-CoV-2 501Y.v2 variant and vaccine implications
      • Do mutations in SARS-CoV-2 variants reduce the functional activity of mRNA-vaccine elicited Abs?
      • IUIS/Immunopaedia-Frontiers Webinar on Immunoregulation and the tumor microenvironment
      • Are current putative COVID-19 vaccines effective against the B.1.351 variants?
      • Phase 2a trial provides evidence for potential pancreatic cancer immunotherapy
      • COVID-19 is associated with increased MAIT cell activation and cytotoxicity
      • Saliva viral load could be a potential correlate of severe COVID-19
    • January
      • Mutations in SARS-Cov-2 B.1.351 variant reduces vaccine induced Ab neutralisation
      • Immuno-metabolism and cognitive decline
      • Ad26.COV2.S is safe and immunogenic
      • SARS-CoV-2-specific Memory B cells persist up to 8 months post infection.
      • Gene editing as a potential sickle cell disease immunotherapy.
      • Not all SARS-CoV-2 mutations lead to reduced antibody neutralisation capacity
      • Development of a serological diagnostic of Johne’s Disease
      • Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
  • 2020
    • December
      • Lack of interference by type I interferons leads to severe COVID-19
      • BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccine efficacy results
      • Potential vitiligo immuno-therapeutic: antigen-specific CAR-Tregs
      • Vaccine elicitation of engineered HIV-specific B cells: inducing bnAbs
      • Which COVID-19 vaccine will be the most effective?
      • SARS-CoV-2 serological assay on-a-chip. 
    • November
      • How does SARS-CoV-2 evade the immune defences?
      • Investigating Ebola immunity using single cell technologies
      • Investigating the role of surfactants during TB using the lung-on-a-chip model
      • Gut Inflammation Linked to a Debilitating Skin Condition
      • Safety and immunogenicity of Sputnik V vaccine
      • SARS-CoV-2 mRNA-1273 vaccine shows signs of potential efficacy
      • Pfizer and BioNTech COVID-19 vaccine
      • The role of Galectin-3 in the tumor microenvironment
      • Developing an oral polio vaccine that does not cause vaccine-associated polio
      • Meningeal-IgA+ plasma cells contribute to CNS-immunity
      • Should we consider aerosol vaccines for COVID-19
      • Testing potential neonatal sepsis drugs using a murine neonatal sepsis.
    • October
      • Granuloma formation during S.mansoni infection: protective or pathogenic?
      • Impact of intermediate hyperglycaemia and diabetes on immune dysfunction in TB
      • NIX is essential for systemic metabolic reprogramming of immune cells mediating tuberculosis protection
      • NIH COVID-19 lecture on SARS-CoV-2 mRNA vaccine
      • Auto-antibody responses to type I IFNs is a clue to severe COVID-19
      • Do lipid bodies play a role in innate immunity?
      • Trained Immunity in Dogs.
      • NIH COVID-19 lecture on SARS-CoV-2 neutralising antibodies
      • Why is flu vaccine induced immunity short-lived?
      • Molecular mimicry: perfect match propels pathologies
      • SAIS/Immunopaedia Webinar: Immunothrombosis & COVID-19
      • Safety and immunogenicity of the SARS-CoV-2 mRNA-1273 vaccine candidate in older age.
      • Genetically modified Lactococcus lactis- A potential microbial therapeutic for acute colitis?
      • IUIS Webinar: Impairment of the immunological and neurological synapses by respiratory viruses
    • September
      • Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate.
      • Why do people with the Dantu blood group have a lower risk of developing malaria?
      • Boosting of antibody responses against the V2 and V3 region of the HIV-1 Env
      • SAIS/Immunopaedia COVID-19 Webinar on Severe vs mild COVID-19 immunity, and intersection between Nicotinamide pathway & COVID-19.
      • A mechanism for severe COVID-19 in patients with obesity and diabetes?
      • HIV Viral reservoir: quality rather quantity matters
      • We need innovative tools to diagnose Coeliac disease
      • IUIS Webinar: Tracking SARS-CoV-2 in Ghana
      • Inclusion of non-spike proteins in SARS-CoV-2 vaccines may be important for the induction of protective T cell memory.
      • CD229 CAR: New therapy for multiple myeloma
      • Immuno-Algeria: Drug hypersensitivity in TB/HIV endemic settings
      • SAIS/Immunopaedia Webinar on BCG & COVID-19
      • Male and female immune responses to SARS-CoV-2 substantially differ.
      • How the Regulator is Regulated: Insight into immune-related Protein holds therapeutic value
      • Immuno-Algeria: Non-invasive allergy biomarkers & next-gen immunotherapies
      • Are Lung microbial products driving hyperinflammation in severe COVID-19?
      • IUIS Webinar: COVID-19 & Immune Compromise
    • August
      • SARS–CoV-2 infection of the placenta
      • Immuno-Algeria: Microbial dysfunction & allergy
      • Can saliva be used to test for antibodies to SARS-CoV-2?
      • SAIS/Immunopaedia Webinar: COVID-19 Vaccines
      • COVID-19 & Multisystem inflammatory syndrome in children
      • Do SARS-CoV-2-specific T cells confer long-lived protection?
      • Immuno-Algeria: Allergic activity of IgE binding molecules
      • Convalescent plasma therapy for COVID-19 is safe.
      • IUIS Webinar: Stress dampens anti-viral immunity
      • COVID-19 in vitro studies: Use the right cell line
      • SAIS/Immunopaedia Webinar: Antibody responses and serology testing
      • Immuno-Algeria: IgE & its receptors as a pharmacological targets
      • SARS-CoV-2 monoclonal antibodies as potential COVID-19 treatment.
      • IUIS Webinar: Predicting survival and severity of COVID-19
      • Treating COVID-19 with immunoglobulins, should we be cautious?
      • RNA-based vaccine BNT162b1 induces robust IgG and T cell immunity
      • IUIS Webinar: Longitudinal COVID-19 Immune Profiling
      • Immuno-Algeria 2020: Cellular components of the allergic response
      • Tissue tolerance in COVID-19
      • Does the D614G mutation in SARS-CoV-2 spike protein result in the virus being more susceptible to neutralization by the host?
    • July
      • Is blocking inflammatory cell movement using chemokine receptor antagonists the way to go?
      • Is there a role of T cells in immune protection to SARS-CoV-2 infection and COVID-19?
      • Immuno-Algeria 2020: Introduction to allergy and molecular diagnosis
      • Rapid decay of IgG to SARS-CoV-2 in people with mild COVID-19
      • The “topology” of the immune response to COVID-19
      • IUIS Webinar: Utilising Ramos B cell engineering to measure SARS-CoV-2 Ab responses
      • Critically ill COVID-19 patients show evidence for extrafollicular B cell activation
      • Immuno-Ethiopia: Xenodiagnosis of Leishmaniasis
      • ChAdOx1 nCoV-19 vaccine is safe and immunogenic
      • Targeting COVID-19 immunopathology using rapamycin
      • Development of a potent SARS-CoV-2 nAb using llamas
      • mRNA Vaccine against SARS-CoV-2 induces robust Ab responses
      • IUIS Webinar: Seeking correlates of COVID-19 protection and pathology
      • Immuno-Ethiopia: Anti-leishmania Immunity
      • COVID-19 & GIT symptoms
      • IUIS Webinar: COVID-19 Monoclonal Abs
      • Aging & COVID-19
      • Immuno-Ethiopia: Sand flies & Leishmaniasis
      • Innate T cells & severe COVID-19
      • Multi-organ damage is a hallmark of severe COVID-19
      • IUIS Webinar: COVID-19 in South Africa
      • Are polymorphisms in the ACE2 locus important for COVID-19 severity?
      • Immuno-Ethiopia: Genetics of Fungal Immunology
    • June
      • Do mutations in the SARS-CoV-2 spike protein enhances viral infectivity?
      • Will the COVID-19 pandemic result in significant neuropsychiatric sequelae?
      • IUIS Webinar: Involvement of C5a-C5aR1 axis in COVID-19 pathology
      • How effective is Dexamethasone for the treatment of patients with COVID-19?
      • SARS-CoV-2-specific IgG and IgM in asymptomatic individuals wane quickly
      • Does breast milk contain SARS-CoV-2?
      • Are blood groups associated with severe COVID-19 respiratory failure?
      • Development of an inactivated vaccine candidate for SARS-CoV-2
      • IUIS Webinar: Understanding Infection and Immunity of SARS-CoV-2
      • IUIS Webinar: Respiratory Immunity and COVID-19
      • Identification of two B cell epitopes that induce neutralising Ab in COVID-19 patients
      • COVID-19 vaccines: can alum based adjuvants improve induction of nAbs?
      • What evidence is there for pre-existing antibody responses to SARS-CoV-2?
      • Is COVID-19 an endothelial disease?
      • A recombinant adenovirus type-5 vectored COVID-19 vaccine appears safe and immunogenic in a first-in-human trial.
      • SARS-CoV-2 monkey model shows protection from re-infection.
      • An exuberant inflammatory host response to SARS-CoV-2 leads to COVID-19.
      • IUIS Webinar: Role of cellular responses in COVID-19
      • SARS-CoV-2 infection in young children and Kawasaki-like disease.
      • No evidence that BCG vaccination can protect against SARS-CoV-2 infection.
      • Do we have more T cell immunity to SARS-CoV-2 than we think?
      • Is the rapid generation of neutralizing antibodies to SARS-CoV-2 good news for preventing reinfection?
    • May
      • The current status of COVID-19 immunology 
      • IUIS Webinar: Trained immunity and BCG vaccination: a tool against COVID-19?
      • A nail in the coffin of (hydro)chloroquine treatment against COVID-19?
      • SARS-CoV-2 found in semen.
      • Can anti-HIV drugs, Lopinavir and Ritonavir, be used to treat patients with severe COVID-19?
      • Can the Cytokine Release Syndrome in COVID-19 patients be treated using CCR5 blocking antibody therapy?
      • IUIS Webinar: Adaptive Immunity in COVID-19
      • Can a Chimpanzee vector vaccine prevent SARS-CoV-2 pneumonia?
      • Getting to the guts of SARS-CoV-2 infection
      • Cigarette smoke triggers increased ACE-2 expression in the lung
      • Respiratory disease and viral shedding in rhesus macaques inoculated with SARS-CoV-2
      • IUIS Webinar: What cancer immunologists are doing about COVID-19 ?
      • BCG induced trained immunity & COVID-19
      • Is there a SARS-CoV-2 receptor (ACE2) expression difference between males and females?
      • Roles of different anti-SARS-CoV-2 antibodies in COVID-19 disease and protection 
      • Exaggerated immune response to Covid-19
      • Can neonates born to mothers with COVID-19 acquire maternal infection ?
      • Mutation in the Spike protein may explain higher infectivity of SARS-CoV-2 and accelerated disease.
      • IUIS Webinar: Global outbreaks – Interferons as 1st responders
      • An inventory of the vaccine candidates to SARS-CoV-2
      • COVID-19: extending or relaxing distancing control measures
      • Is a self-amplifying RNA SARS-CoV-2 lipid nanoparticle a good vaccine candidate?
      • SARS-CoV-2 transmission exploits existing secretory pathways in the nasal cavity: a vaccine/drug target? 
      • The role of complement in COVID-19 pathogenesis.
    • April
      • Scientific Response to COVID-19 Video
      • Can two FDA-approved drugs be re-purposed to clear SARS-CoV-2 infection?
      • Should we consider SARS-CoV-2 human challenge models for vaccine testing ?
      • Mask wearing to reduce the spread of COVID-19
      • Development of inactivated SARS-CoV-2 vaccines
      • Cytokine Release Syndrome & COVID-19
      • COVID-19 Antibody Immunology Video
      • Uncertainty is hampering doctors’ ability to treat COVID-19
      • Detection of SARS-CoV-2 nAbs in cats
      • Susceptibility of domestic animals to SARS-Cov-2
      • Indian population could have intrinsic immunity to resist COVID-19 challenge
      • Viral dynamics in mild vs severe COVID-19
      • SARS-CoV-2 transmission and mask wearing.
      • Convalescent sera option for containing COVID-19
      • Potential SARS-CoV-2 & COVID-19 Vaccines
      • COVID-19 Vaccinology Videos
      • Chloroquine treatment and COVID-19
      • Exhaustion of antiviral NK and CD8 T cells in SARS-CoV-2 infection
      • The different clinical characteristics of COVID-19 between children and adults.
      • Safety considerations in laboratory practice when testing specimens from patients suspected or infected with SARS-CoV-2
      • A serological assay to detect SARS-CoV-2 seroconversion in humans
      • Where did SARS-CoV-2 come from?
      • Faecal shedding of SARS-CoV-2 
      • COVID-19 spurs interest in preprints and improves scientific collaboration
      • BCG & COVID-19
      • Potent neutralizing antibodies isolated from COVID-19 patients
      • The potential benefit of high-dose intravenous Ig in severe COVID-19 
      • SOLIDARITY TRIAL: Testing existing drugs to treat COVID-19
      • Why is COVID-19 so mild in children?
      • SOLIDARITY TRIAL: WHO COVID-19 treatment trial
    • March
      • Could blood groups influence COVID-19 disease severity?
      • Why are hypertension and diabetes patients at high risk of severe COVID-19?
      • The Origin of SARS-CoV-2
      • Does COVID-19 have a seasonal pattern?
      • Broad-spectrum Antiviral Inhibits SARS-CoV-2
      • Hypothetical pathogenesis of SARS-CoV-2 infection in humans
      • COVID-19 - Cytokine storm syndromes and immunosuppression
      • WORLD TB DAY: COVID-19 & TB
      • Kinetics of Immune Response in a Mild COVID-19 Patient
      • Immuno-Ethiopia: Fungal epidemiology and immunology
      • Immuno-Ethiopia: Malaria Highlight 2
      • Immuno-Ethiopia: Malaria Highlight 1
      • Single-cell RNA-Seq of BAL samples from COVID-19 patients
      • Type I interferon co-stimulation of MAIT cell function
      • The (Un)usual Suspect-Novel Coronavirus Identified
    • February
      • Murine model of coeliac disease
      • miRNA carried by NETs modulate macrophage function
      • Does mumps immunity induced by 2 doses of MMR wane in adulthood?
      • Fever: A positive regulator of Th17 mediated inflammation
      • T cells altered by CRISPR may be safe to use in cancer patients
      • DENV-infection induces two major CD8 T cell memory subsets
      • Repurposing of a drug for alcoholism to treat cancer
    • January
      • Measles induced immunological amnesia
      • SEPSIS is WANTED!
      • Discovery of novel cancer signalling mechanism
      • Macrophages and Cervical Cancer: What's going on with the microenvironment ?
      • How DNA outside cells can be targeted to prevent the spread of cancer
      • Solving the puzzle of IgG4-related disease, the elusive autoimmune
      • How the rice blast fungus “eats” its own cell wall to launch an attack
      • Can intravenous-BCG prevent M.tb infection ?
  • 2019
    • December
      • How does group A Streptococcus evade immunity?
      • TB biomarker based on anti-Ag85B and 4 inflammatory molecules.
    • November
      • Immuno-Jaipur Highlight: Primary immunodeficiencies
      • Immuno-Jaipur Highlight: Clinical viral immunity
      • Immuno-Jaipur Highlight: MHC and Transplantation Immunology
      • Immuno-Jaipur Highlight : Part 2 of Day 4
      • Immuno-Jaipur Highlight : Day 4
      • Immuno-Jaipur Highlight: Part 2 of Day 3
      • Immuno-Jaipur Highlight of talks by Abul Abbas
      • Immuno-Jaipur Highlight: Insights into innate and adaptive immunity
      • IUIS-IIS-FIMSA-Immuno-Jaipur Report
      • IUIS Beijing ICI 2019
      • IDA Highlight: What’s New in anti-HIV humoral immunity.
      • IDA Highlight: Current state of malaria vaccines
    • October
      • IDA Highlight: Scanning the TCR repertoire to inform new TB vaccine targets
      • IDA Highlight: Possible barriers and opportunities for HIV cure
      • IDA Highlight: Not all levels of malaria exposure induce the same anti-malarial  immunity
      • IDA Highlight: Immune responses to TB vaccines
      • IDA Highlight: CD4 T cells in HIV infection
      • Career Advice from IDA faculty that were once previous IDA Scholars
      • Lipid profiles key step to preventing breast cancer metastasis through epithelial-mesenchymal transition
      • The Vaccinology course, if you are in the vaccine-world, you shouldn´t miss it!
      • Investigating the immunological composition of the Kidney
      • CD27 expression identifies Th17 cells with high stemness properties
    • September
      • New fungus-derived antibiotic: relief in sight for immunocompromised people
      • HIV RV144 vaccine induces better responses in SA compared to Thailand
      • Rethinking HIV remission strategies: end of the road for anti-α4β7 ?
      • GLA-SE promotes superior Tfh expansion than Alum
      • Class-switch recombination of antibodies occurs prior to germinal center formation.
      • Can anti-α4β7 really “cure” SIV infection in ART interrupted NHPs ?
      • New insights into the role of HPV oncoproteins and immune response in cervical cancer
      • Did you know neutrophils can help to form gallstones?
    • August
      • Can vaccinating cats against their own proteins reduce cat allergies in humans?
      • Use of future liposomal cancer oncology treatment
      • What other disease affect individuals with olive pollen allergies?
      • The Immune Function of Osteoclasts
      • TAK-003 induces functional DENV cross-reactive cellular immmunity
      • Wild is better: in-bred mice born to wild mice resemble human responses
      • Do NK cells play an important role in anti-Trypanosomiasis immunity?
      • Are MAIT cells detectable in lymph?
      • Does S. mansoni treatment affect HIV susceptibility?
    • July
      • Investigating the HIV viral reservoir during acute infection 
      • How does BCG affect early innate immune responses?
      • Sex associated differences to flu vaccination: role of estradiol?
      • Propagation of α-synuclein from the gut to brain – new causation for Parkinson’s disease? 
      • Have you heard of Mycetoma ?
      • How does plasmodial hemozoin contribute to cerebral malaria pathogenesis?
      • Are neutrophils in the tumor microenvironment friend or foe?
      • Animal models to measure mucosal innate immunity: zebrafish vs mice.
    • June
      • Development of natural murine model of  Cryptosporidiosis
      • Does whole cell pertussis vaccination skew infection induced Ab profiles?
      • Is Yellow fever vaccination safe for HIV+ individuals?
      • The emerging role of IL-26 in fighting against intracellular microbes
      • T cell activation as a potential surrogate marker for TB treatment efficacy.
      • Does HIV-env vaccination strategy affect the recognition pattern of IgG responses?
      • Does dysbiosis of the GIT microbiome enhance the neutrophils survival and chronic inflammation in HIV+ individuals?
      • Dual BCR and TCR co-expressing lymphocyte could play a role in T1D pathogenesis.
    • May
      • M.tb resistors: M.tb uninfected or atypical IFN-𝛾-independent M.tb immune responses ?
      • Course Highlight: 5th Vaccinology in Course
      • Immunoinformatics Mexico 2019: Immunologic plasticity, defense lines.
      • Immunoinformatics Mexico 2019: Part Two
      • Immunoinformatics Mexico 2019: Part One
      • Aiding Tuberculosis vaccine studies with the use of a mycobacterial growth inhibition assay
      • Further Support of the Emerging “Immunologic” Hypothesis in Mood and Eating Disorders
    • April
      • Immunopaedia goes to the XIII World Immune Regulation Meeting
      • Evolution of flu-vaccine induced B cell responses
      • Antiviral pathways induced in the RV144 vaccine trial
      • How are CD8 responses against the malaria liver stage antigens primed ?
      • Contributions to the understanding of the cellular immune response elicited by Brucella canis
      • IL-7Rαlo KLRG1hi cells are not always short lived effector cells
      • Dual bNAb therapy can maintain HIV viral suppression
      • A first-in-human antibody–drug conjugate: Hope for patients with advanced solid tumours?
    • March
      • Targeting the metabolic profile of latently infected macrophages as a potential treatment for HIV  
      • PD-1/PDL1 pathway in the maintenance of maternal-foetal immunotolerance
      • How does the complement cascade result in pore formation in Lampreys
      • HIV complications: inflamma-aging or increased activation ?
      • Does BCG improve de novo malaria immunity ?
      • Hematopoietic stem cell transplantation cures HIV
      • Do neutrophils play a role in age-associated increase in flu mortality?
      • Do NK cells play a role in vaccine induced humoral immunity ?
      • ICOS: is it essential for Treg-IL10 expression in the colon?
    • February
      • How does IL-27 attenuate autoimmune neuroinflammation?
      • CNS-neuroinflammation: not all myeloid cells are responsible
      • Immunosenescence: how does it affect vaccine Ab responses ?
      • Recurrent Strep throat: when TFH cells “turn on” you
      • TB episode following PD-1 blockade
      • Can a vaccine prevent ZIKV associated fetal abnormalities ?
      • Does mucosal BCG vaccination induce “protective” immunity ?
      • Are CD8+ and DN MAIT cells distinct populations ?
    • January
      • What can ZIKV-CD8 T cells do ?
      • Can some Tfh cells produce IFN-𝛾 ?
      • Have you heard of the ESAT-6 free IGRA ?
      • Are distinct monocyte subsets associated with severe Chagas diseases?
      • Does HIV superinfection induce an additive or synergistic Ab effect?
      • Where do memory B cells get reactivated?
      • Strain specific host restriction of recurrent UTIs
  • 2018
    • December
      • TLR-agonist and Salmonella are potential antimelonoma immunotherapy
      • Plasmablast formation: which T helper phenotype is important?
      • Organ specific replenishment of tissue resident macrophages
      • IDA Highlights: Innate signatures of HIV vaccines
      • IDA Highlights: TB vaccines
      • IDA Highlights: HIV Immunity
    • November
      • What's behind Eosinophilic Esophagitis?
      • IDA Highlights: Malaria
      • IDA Highlight: TB is a complex disease
      • IDA Highlights: Immune responses at mucosal sites
      • We are at the IDA this Week
      • Intestinal helminth co-infection promotes control against lung migrating parasites
      • Characterisation of porcine conventional DC subsets
      • Where do uterine NK cells during pregnancy come from?
    • October
      • Understanding follicular CD8 T cells during SIV infection
      • Are alveolar macrophages M1 or M2 polarised?
      • Identifying disease-associated populations in the age of big data
      • IgD: the lesser known antibody 
      • MAIT cell dysfunction during primary sclerosing cholangitis
      • How does bacterial-viral co-infection impact anti-viral immunity?
      • Antibodies and TLR7 agonist delays HIV viral rebound
      • Lower efficacy of tumour immunotherapy in obesity is due to elevated Leptin 
    • September
      • 2018: The year of hope for TB vaccines
      • Is CD153 essential for M.tb control ?
      • Omentin-1 rescues inflammation-induced osteoporosis
      • New hope from chronic HBV patients: non-replicative Ad-HBV vaccine
      • Have you heard of analytic treatment interruption of HIV ART?
      • A novel function of the antihelminthic drug Praziquantel: new strategy for combatting schistosomiasis
      • What is the incubation period of TB?
    • August
      • E-cigarettes may not be a healthier alternative to traditional cigarettes.
      • α4β7-MAdCAM interaction promotes HIV replication.
      • Comparing H56 responses in NHP and humans using mathematical modelling.
      • Fatal SFTSV is associated with defective B cell responses
      •  Potential treatment for metastatic colorectal cancers: T cell engaging bispecific antibodies
      • How do γδ T cells control humoral immunity ?
      • Can antibiotic treatment improve Rotavirus immunogenecity?
      • Clade C RV144-like vaccine is immunogenic.
      • Can B cell responses predict resolution of Lyme Disease?
    • July
      • Can profiling CD8 T cell responses from Ebola Survivors improve vaccine design?
      • Can platelets directly kill Plasmodium sp. ?
      • Can viral Immunogenicity govern DENV epidemiological fitness ?
      • How do tuft cells induce Type 2 Responses?
      • CD32: marker of HIV reservoir?
      • New Hope for TB Vaccines
      • HIV vaccine induces similar responses in humans and rhesus macaques.
      • Ontogeny of MAITs
      • Public Antibody Clonotypes observed in HIV+ individuals.
    • June
      • Another use for BCG, potential Diabetes cure?
      • Can testosterone regulate B cell numbers?
      • Initial Immune Responses to TB in the Human Lung
      • Antibody-based vaccine protects against 31% of HIV isolates
      • Natural infection improves breadth of vaccine induced memory
      • MGIAs: potential role of trained immunity ?
      • ALAI/SMI Highlight:  Have you heard of IL-40?
      • Resident CD8+ T cells restrain HIV replication in elite controllers 
      • Latin American Immunology Congress, a cocktail of scientific breaking news.
      • ALAI/SMI congress: Hosts a Nobel Laureate and the 1st Iberoamerican Flow Cytometry Meeting
      • Immunopaedia goes to the Latin American Immunology Congress
      • ECTS2018 – Where scientific research and clinical practice meet
      • How does alum block induction of Th1 cells ?
    • May
      • Does CXCL17 contribute to protection against herpes ?
      • Vaccine induced monocyte activation contributes to decreased risk of SIV acquisition
      • Tuft cell tropism may aid norovirus pathogenesis
      • First Animal Model of Rasmussen’s encephalitis
      • Engineering IL-2 cytokine-receptor complexes to improve cancer immunotherapy
      • Reduced Flu severity due to high fibre diet
      • CD4 T cell positioning in TB granulomas matters
      • Have you heard of trained immunity?
      • Human mAbs protects against Zika Neuropathology in Mice
      • Commensal bacteria leverage IgA during colonisation
      • Cyto2018 Highlight: Phenotyping DCs using 30 markers.
      • Cyto2018 Highlight: Immune Clock of Pregnancy
    • April
      • Have you heard of TPMs?
      • Metabolic reprogramming: Novel strategy to improve cancer immunotherapy
      • Do monocytes contribute to heamolytic ureamic syndrome?
      • How do mesenchymal stem cells alleviate severe asthma symptoms?
      • Improved tetramer staining protocol detects functional T cells with low affinity TCRs 
      • Harmless γδ T cells associated with Corynebacterium sp. can be harmful during immune dysregulation
      • Cancer Immunotherapy is associated with changes in innate immunity
      • Paratuberculosis in Cattle: Differences in WC1+ γδ T cells responses to stimulation with PPD-J
      • Serum IgA induced by commensal microbes protects against sepsis
      • Improved T cell detection by Peptide-MHC dodecamers compared to tetramers
    • March
      • Not all RV144 vaccine induced IgA responses are bad.
      • Profiling MAITs during Multiple Myeloma
      • How does anti-TNF treatment affect TB granuloma formation?
      • Immunoregulatory effects of Vitamin B5 during M.tb infection
      • Oral vs intradermal BCG, what's the difference?
      • Which cells contribute to immunity against vaginal Zika infection ?
      • Can CXCL4 contribute to autoimmune pathology?
      • 5GFTB Highlights: Human TB Challenge, is this possible?
      • 5GFTB Highlights: Why is a new vaccine against TB important?
      • 5GFTB Highlights: MTBVAC potential BCG replacement
      • Article Highlight: Differentially Expressed Host linc RNA and mRNA in HIV-1 and HIV-2 Infection (Santanu et al., 2018)
    • February
      • 5GFTB Highlights: Can we immunologically distinguish LTBI, EPTB and PTB
      • 5GFTB Highlights: Can we induce BCG-mediated long term innate immunity
      • 5GFTB Highlights: Recombinant BCG-Esx1 can induce CD8 T cell responses
      • CD45.1 vs CD45.2 B6 mice more than an isoform difference.
      • Potential therapeutic use of H. pylori for asthma
      • Local signals matters: implication for CD8 T cell function against Leishmania
      • Influenza-specific lung resident CD8+ T cells maintain diverse TCR profiles
      • Influenza-specific lung TRM maintain diverse TCR profiles
      • ILCs homeostasis in Psoriatic Arthiritis
      • MAITs respond differently to ZIKV and DENV
      • H5VLP-GLASE unlike H5VLP-alum induces both Ab and T cell responses
      • Non-cytotoxic function of HIV-specific rectal CD8+T cells
    • January
      • Measuring T cell proliferation using the “Warburg” effect.
      • Re-developed live attenuated Cholera vaccine, is it safe?
      • Is kick-and-kill HIV cure strategy achievable?
      • T-bet expression negatively affects T cell lung homing during TB
      • T follicular helper cells are essential for generating nAb during chronic-infection.
      • HIV Env immunogens elicit broad antibody responses in animal models
      • Immunological T and B cell Diversity of the Human Penis
      • How does hyperglycemia lead to aggressive cancer?
      • We need new HAB/HBV vaccine strategies for HCV/HIV infected individuals.  
      • Dengue specifc-CD8 T cell responses but not Abs provide protection against Zika
      • Patho-physiological implication of NET in COPD patients
      • Phase 1 Zika vaccine trial shows promise
      • SAHGP Pilot: Southern Africans are more diverse than expected
  • 2017
    • December
      • Whole M.tb inherently induce highly differentiated T cells compared to H56 vaccination
      • Kai 1 and Kai 2, new Dog Erythrocyte Antigens: implications for clinical practice
      • Expression of CD40L by CD8 T cells promotes autologous activation and differentiation
      • Vaccine induced T cell immunity, antigen localisation in bacterial vector matters
      • Functional antibody immunity 40 years post Ebolavirus exposure
      • Immunomodulatory effect of lactic acid on the female reproductive tract
      • Elevated Th17 cells in “healthy” overweight children
      • Transphagocytic CD4+ T cells are true APC capable of inducing functional CD8 memory cells
      • Potential serological test capable of distinguishing Zika from Dengue infections
      • RTS,S/AS01E induces robust central memory responses to HBsAg but not to CSP
    • November
      • CD161+CD4+ T cells depleted at the Cervix during HIV Infection
      • Regulatory T cells help prevent CMV reactivation
      • Asymptomatic Zika virus infection protects from re-infection
      • PD-1-based immunotherapy affected by gut microbiome
      • Link between schistosomiasis and HIV susceptibility
      • IL-10+ Th1 T cells associated with reduced malaria parasitemia
      • Is HIV becoming more resistant over time?
      • Pre-diabetes associated M.tb-specific T cell dysfunction
      • Insight into immune activation caused by Ebola virus
      • Highlights from the Infectious Disease (ID) Week 2017 Conference
      • Effect of BCG vaccination on HIV-exposed infants
      • Mechanism behind malaria-induced autoimmunity
      • Lung on a chip model recapitulates lung cancer pathology and therapy
    • October
      • Antibody cocktail to prevent Zika infection in pregnant women
      • Antibody-drug dual combination to fight cancer
      • Block-and-lock strategy to cure HIV
      • Memory responses are not restricted to immune cells
      • Pharmacological treatment of lymphedema
      • How effective are anti-TNF-α agents in treating sarcoidosis?
      • Regulatory T cells delay clearance of malaria through CTLA-4
      • Role of horsepox in smallpox vaccine
      • Short chain fatty acids improve inflammation of the eye
      • Probiotics induce double-positive intraepithelial lymphocytes
      • Environmental factors associated with asthma development
      • CXCL13 predicts development of HIV-specific antibodies
      • HPV-positive cancer cells are dormant in low oxygen conditions
    • September
      • IL-4–producing B cells shift T cells to Th2 responses
      • Type I interferons are important in anti-helminth Th2 immunity
      • Trispecific antibody for HIV therapy
      • Antibodies protect against cytomegalovirus infection
      • Investigating HIV RNA expression during antiretroviral therapy
      • Gut bacteria induce pro-inflammatory response in MS
      • Severity of leishmania infection depends on time of day
      • Multi-site injections enhance immune responses
      • Histamine releasing factor makes host vulnerable to malaria
      • Plasmodium infection promotes bone loss
      • Antibodies with incomplete neutralization protect against SHIV
    • August
      • Inflammation associated with chronic fatigue syndrome
      • Next-generation RTS,S-like malaria vaccine
      • Zika virus replication in female genital tract
      • HIV Nef protein implicated in cardiomyopathy
      • Interaction between microbiome and urogenital schistosomiasis
      • Terminal differentiation of T cells during CMV & HIV infection
      • Role of IL-7 receptor in tuberculosis
      • Langerhans cells affect HIV transmission
      • Breastfed children less susceptible to asthma attacks
      • Cerebral cavernous malformations enhanced by microbiome
      • Child maintains HIV remission without drugs
      • Garlic treats dengue virus inflammation
    • July
      • Candidate heroin vaccine effective in primate model
      • Helminth protection by innate Type 2 immunity
      • Diabetes vaccine in sight
      • Cow immunizations generate broad HIV antibody responses
      • Resident T cells improve melanoma prognosis
      • Microorganisms in the eye protect against infection
      • Gonorrhoea superbug on the rise globally
      • Reprogrammed T cells kill cancer
      • Malaria-induced anaemia reinforced by treatment
      • Immunopaedia, the Official IUIS Learning Site
      • Optimizing HIV immunization strategies
      • High salt intake linked to graft rejection
      • The nutritional consequence of HIV-helminth coinfection
      • mTOR implicated in the onset of asthma
    • June
      • A Broad Overview of HIV Treatments and Cures
      • HPV E7 protein downregulates antitumour immunity
      • Cancer-killing viruses: the future of cancer therapy?
      • Vaginal Microbiome Affects HIV Prevention
      • Sensitive Zika virus diagnostic method using whole blood
      • Deletion of TB protein eliminates cell heterogeneity
      • Meat Allergy Develops from Tick Bite
      • Dorsal foreskin cutting for effective HIV prevention
      • Type III IFNs in Hepatitis E persistence
      • Marijuana May Decrease ART Adherence
      • Preterm births alter ATP production and immunity
      • Conventional antibody can neutralize HIV
      • HIV PrEP Linked to Kidney Function
    • May
      • Allergy and asthma across generations
      • Microbiota in T cell survival
      • Early Introduction of Peanuts Prevents Allergies
      • MyD88-mediated cells against C. rodentium identified
      • Cross-reactive antibodies for Ebola vaccine
      • Engineered CD8 T cells flush out HIV reservoirs
      • Targeting an integrin as a potential HIV therapeutic
      • Marginal zone B cells in cholesterol control
      • HIV immunogen based on precursor antibodies
      • MHC Ib molecule protects against TB infection
      • Broad antibodies from HIV-infected individuals
      • Zika virus persists in cerebrospinal fluid and lymph nodes
      • How Tregs control liver damage
    • April
      • GM-CSF and neuroinflammation
      • Glycosylation consensus to aid HIV immunogen design
      • Recycling of B cells in the humoral immune response
      • Cell-to-cell HIV transmission evades antibody responses
      • Application for CRISPR in muscular dystrophy
      • Alere HIV Combo Rapid Test
      • HIV escapes by novel mechanisms
      • IL-17RA deficiency and susceptibility to pathogens
      • Microvilli in T cell activation
      • Asthma increases susceptibility to influenza
    • March
      • Identical viruses form HIV reservoir
      • Dysfunctional B cell subsets in TB patients
      • HIV vaccine design with less mutated antibodies
      • Lab mice may be too clean to use in studies
      • Combination of 2 antibodies controls HIV replication
      • CD8 T cells are important for Zika virus control
      • New autoimmune disease driven by thymic tumour
      • Malaria vaccine trial with promising results
      • Road to an effective HIV immunogen
      • Mycobacterium tuberculosis diversity
      • Novel cell population reduces response to tumours
      • Polyfunctional antibodies in the control of HIV
      • Neutrophils aid in immune tolerance during pregnancy
      • Probiotic lotion as eczema treatment
    • February
      • Antibody that can control HIV replication
      • Important role for antibodies in TB infection
      • Mucosal cells enhance HIV entry into CD4 T cells
      • Novel mechanism for anti-cancer drug
      • Changes in gut microbiome in Inflammatory Bowel Disease
      • Functional B cells needed to prevent preterm birth
      • Antibody resistance does not play a role in mother-to-child-transmission
      • Using chemokine CXCL13 as a biomarker of germinal centre activity
      • Reason why immunotherapy does not work for all cancers
      • Characterization of novel antibody that recognizes HIV trimer
      • International Remote Conference Highlights: Establishment of memory CD8 cells to influenza
      • International Remote Conference Highlights: Antibody response to malaria in Burkina Faso
    • January
      • International Remote Conference Highlights: Can HAART be used to cure HIV?
      • Rapid evolution of the infant microbiome after birth
      • No role for CD4 T cells in shift from latent to active TB
      • Evidence for antibodies in control of HIV infection
      • Not all CD8 T cells have cytotoxic effects
      • 2nd Annual International Remote Conference: Science and Society
      • Role of T cells in Zika virus infection
      • Effective mechanism to kill human viruses
      • Different gut microbes present depending on diet
      • No correlation between Vitamin D levels and vaccine responses
      • Changes in CD8 T cells during viral infection
      • Traits associated with the production of broadly neutralizing antibodies
  • 2016
    • December
      • Novel mechanism reveals how leishmania evades immune system
      • Gut microbiota suppress liver cancer
      • Ebola vaccine confirmed to be highly effective
      • Chikungunya virus vaccine using an insect virus
      • Characteristics of HIV which affect antibody recognition
      • The adverse effects of Zika virus on infants
      • Using CARs to kill HIV
      • Unique T cells compartmentalize in lymphoid sites
      • Using nanoparticles in HIV immunogen design
      • The link between malaria and cancer
      • Gut microbiota influences pathogenesis of Parkinson’s disease
      • Is an HIV vaccine possible?
      • Insights into how hemolysis leads to susceptibility to infection
    • November
      • Th1 response leads to effective antibodies against influenza
      • Targeting essential TB enzyme may lead to novel treatments
      • Treating helminth infections boosts immune system
      • Toll-like receptor helps nematodes avoid pathogens
      • Infants can produce anti-HIV antibodies with minimal somatic hypermutation
      • Antibodies from Ebola survivor have potent anti-viral activity
      • The microbiome has anti-tumor effects
      • Understanding the organization of TB-associated granulomas
      • Using cell-specific knock-outs to study the function of genes
      • Mycobacterium tuberculosis tricks body into autoimmunity
      • HIV R4P Highlights: Dendritic cells which capture HIV in Female Reproductive Tract
      • HIV R4P Highlights: Inducing T cells in an HIV Vaccine
    • October
      • HIV R4P Highlights: HIV superinfection does not increase antibody breadth
      • HIV R4P Highlights: New antibody lineages against HIV high mannose-patch
      • HIV R4P Highlights: BV increases risk of HIV acquisition through neutrophils
      • HIV R4P Highlights: Children frequently make HIV-specific broad antibody responses
      • HIV R4P Highlights: Interview with Prof Thumbi Ndung'u
      • HIV R4P Highlights: α4β7 antibody and ART: a novel HIV therapy
      • IgA antibodies found in women taking PrEP
      • The role of TNF and aging in susceptibility to infection
      • A combination of worms and bacteria may be good for your health
      • Immunological memory in the Mucosa
      • Neutrophils and radiation therapy working together to fight cancer
      • Mosquitos with fungus are more susceptible to malaria parasites
      • Understanding the skin phenotype of children with eczema
    • September
      • Treating HIV with the power of an antibody
      • Possibility of one vaccine to prevent Zika and Dengue viruses
      • ICI 2016 - What leads to HIV progression in children?
      • ICI 2016 - Parasitic worms in the treatment of chronic asthma
      • ICI 2016 - Potential new diagnostic tool for TB in children
      • ICI 2016 - The role of complement in fighting malaria in pregnancy
      • ICI 2016- Mycobacterium tuberculosis at the granuloma level in the human lung
      • ICI 2016 - What is the link between house dust mites and allergic disease?
      • ICI 2016 - Reversing Schistosomiasis Tissue Fibrosis
      • ICI 2016 - The Future of a More Effective HIV Vaccine?
    • August
      • Reflecting on AIDS 2016
      • Vaccine: Protective Measures Against Chlamydia Discovered
    • July
      • Immunopaedia goes to the 21st International AIDS Conference
      • Treating AIDS in 2016: New drugs for the future
      • Financing the Response to HIV: Show Us the Money
      • Progress in HIV Vaccines and the Road to the Clinic
      • AIDS 2016: Towards an HIV Cure
      • Regulation of IL-25 levels provides protection against clostridium difficile infection
      • Injection drug use and susceptibility to HIV and co-morbidities
      • Is there a link between loneliness and Inflammation?
    • June
      • Do Mosquito bites help viral infections?
      • Can we tolerate an inhaled vaccine as a way to improve BCG efficacy?
      • A new genetic approach for diagnosing Common Variable Immunodeficiency
      • Inflammatory markers during pregnancy is linked with autism
      • Possible mother-to-child transmission route for Zika virus discovered
      • HIV uniquely impacts on gut microbial metabolism
      • A potential target for HIV reactivation discovered
      • A promising new treatment for systemic lupus erythematosus (Lupus)
    • May
      • Immune Ontogeny and the microbiome
    • April
      • A New Rapid Antigen Test for Human Bocavirus 1 (HBoV1)
      • Antigen Delivery to the Draining Lymph Nodes is a Key to Intradermal Vaccination Efficacy
    • March
      • Trivalent Inactivated Poliovirus Vaccine (IPV) is Non-Superior to Live-Attenuated Oral Poliovirus Vaccine
      • Intact Ovine Immunoglobulin (EBOTAb) to Treat Ebola Virus Infection?
    • February
      • A novel immune mechanism of killing HIV infected cells
      • Protecting Mucosal immunity in HIV positive people with combined CCR5/Integrase Inhibitors
    • January
      • Solving the 50-year-old riddle: the link between Plasmodium falciparum Malaria and Endemic Burkitt’s Lymphoma
      • Why older people may succumb more readily to pneumonia
      • Does Chlamydia infection result in increased HIV susceptibility?
      • A new theory to explain autoimmunity: The Altered Glycan Theory of Autoimmunity
  • 2015
    • December
      • Success of passive HIV immunization?
      • Herd Immunity: immunology meets public health
      • Associations between infant chubbiness and Dengue Haemorrhagic Fever
      • Do we need to re-think vaccine strategies to elicit anti-HIV antibodies?
      • SIV infection of Tfh Cells in monkeys
      • Can wearing silver damage your health?
      • Immune and viral events leading up to acute Infectious Mononucleosis
      • World AIDS Day Message
    • November
      • Genetically modified commensal bacteria used as a possible HIV vaccine adjunct
      • Prevention of Mother-to-Child HIV transmission in African children in the first year of life
      • Levels of PD-L1 Expression on target cells helps to establish viral latency
      • Microbial Gut diversity predicts immune status during HIV-1 infection
      • Stasis of CD8+ T Cells in the brain is a Signature of Cerebral Malaria
      • Diversity of lipid envelopes in Mycobacterium tuberculosis
      • A new reservoir of HIV found within peripheral Vδ2 T cells
      • A new marker denotes exhausted CD8+ T cells during chronic viral infections
      • New antibodies that target sugars on the HIV-1 envelope
    • October
      • Nucleoside reverse-transcriptase inhibitors (NRTIs) as first-line ART in African Children
      • What causes the high mutation rates of HIV-1 in the human body?
      • Is Adipose Tissue a viral reservoir?
    • September
      • Combination Antibiotic and Pidotimod Therapy against Pneumonia
      • Extracellular vesicles as a vaccine candidate against Staphylococcus aureus infections
      • New Mechanism underlying Rheumatoid Arthritis Pathogenesis
    • August
      • Novel model provides quantitative explanation of CD4+ T Cells pathway in vivo
      • Pregnancy Induces Activation of Aged Dormant Muscle Progenitor Cells
      • The microbes within us – the microbiological niche of the lungs
      • TLR5-mediated sensing of gut microbiota has a role in response to flu vaccine
  • 2014
    • November
      • Airborne origins for Kawasaki disease
      • HIV integration into the host DNA is not a random event.
      • New model for treatment of RSV
      • Activation of HIV transcription in latently infected cells
      • A link between the gut microbiome and brain function?
      • Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer
      • Can environmental non-TB mycobacteria interferes with immunity to TB?
      • Dissecting tumor myeloid compartments to reveal APC critical for T Cell immunity
    • October
      • Fruit Bats and Flu
      • Efficient 1-step radiolabeling of monoclonal antibodies for targeted radioimmunotherapy treatment of cancer
      • Protein kinase D2 amplifies T cell receptor–stimulated signaling in naïve CD8+ T cells
      • Characteristics of memory B Cells following HPV vaccination Immunity
      • Antibiotic treatment failure in four common infections- A primary care 1991-2012: longitudinal analysis
      • Neutrophil crawling in capillaries- a novel response to MRSA
      • Immune-suppressant vaccine c blocks SIV infection in macaques
      • Short-term changes in HIV viral load and CD4+ cell count
    • September
      • Group B Strep selected and fixed through use of tetracycline
      • Streptococcus pneumoniae forms microlesions in myocardium, disrupting cardiac function
      • CD45 ligation expands Tregs by promoting interactions with dendritic cells
      • Club cells – identified in Influenza pathogenesis
    • August
      • EBV specific cytotoxic T Cell clones can transiently control EBV infection
      • Mother–Infant HIV Transmission a review on antibody protection
      • Eradication of metastatic mouse cancers by suppression of myeloid-derived cell
      • Histone Deacetylase Inhibitors mark the ability of cytotoxic T cells to eliminate HIV
      • A link between penicillin treatment in newborn infants and obesity
      • Is there a link between Infertility and promotion of Sexually transmitted Infections?
    • July
      • Efficacy of HPV vaccination in HIV positive adolescents and young adults
      • Infectious Disease in Africa Symposium
      • Cannabidiol-possible treatment option for acne
      • Together muscularis macrophages and enteric neurons regulate gastric motility
      • Lopinavir/Ritonavir-based ART vs Efavirenz-based ART for the prevention of malaria in pregnancy
    • June
      • Viral reservoirs limited by ART
      • The role of Cas1 and 2 proteins and immunity
      • T. gondii ligand shown to promote inflammatory monocytes and provide resistance to bacterial infection
      • Characterization of pandemic influenza immune memory after vaccination or infection
      • First-line boosted protease inhibitor regimen remains effective after virologic failure
      • ART in acute infection limits viral reservoirs
      • Kaposi Sarcoma treated with pegylated interferon
      • Broad-spectrum anti-biofilm peptide targets cellular stress response
    • May
      • HIV sexual transmission risk among serodiscordant couples
      • Renal function of participants in tenofovir study- Thailand
      • Varicella Zoster Virus infection: Bad in adults
      • Prostate cancer incidence among HIV-positive and HIV-negative men
      • Beta-catenin–regulated myeloid cells determine wound healing
      • Vaccine-induced myeloid cell population dampens protective immunity
    • April
      • Risk of Melanoma in People with HIV/AIDS
      • New experimental vaccine looks promising for Dengue Fever
      • New TB drug combination to enter late-stage testing
      • Control of Malaria-Induced Inflammation in Children is Dependent on Exposure.
      • Mucosal and endotracheal delivery of RSV peptide prevents nasopulmonary infection
      • Clec12a regulates inflammation in response to cell death
      • Results from a novel flu vaccine
    • March
      • Using immunomics to find vaccine antigens for schistosomiasis
      • South African treatment guidelines should use viral load, not CD4 count for greater success
      • T cell differentiation regulated by methyltransferase G9A during murine intestinal inflammation
      • Understanding molecular evolution of HIV and ART
      • Inhibition of calcineurin abrogates whereas inhibition of mTOR promotes Regulatory T Cells
    • February
      • Neuronal ferritin heavy chain and opiate abuse affect HIV-associated cognitive dysfunction
      • Agonistic induction of PPARy shown to reverse emphysema
      • Treating rhematoid arthritis with peptide-specific CD8+ regulatory T cells
      • Tolerance or resistance to HIV infection? Which is it?
      • UTI treatment requires a coordinated phagocytic response
      • Memory regulatory T cells reside in human skin
      • T cell repertoire following autologous stem cell transplantation for multiple sclerosis
    • January
      • Sex difference noted in response to influenza vaccine
      • Normalizing glycosphingolipids restores CD4+ T cells function in lupus patients
      • Reliability and clinical relevance of HIV drug-resistance testing at low viraemias
      • Microbiota helps regulate behaviour in Autism Spectrum Disorders
      • Thibela TB study - a trial of mass Isoniazid preventive therapy for tuberculosis control
      • A systematic review and meta-analysis of long-term immune responses to vaccination in HIV
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