European Researchers collaborated to develop a new strategy to treat cat allergies in human subjects by immunizing cats against their own major allergen. The vaccine targeting Fel d1 in cats will affect the allergic response by...
August 2019
Use of future liposomal cancer oncology treatment
27August Researchers in South Korea have identified a new method for treating difficult cancers using state-of-the art liposome technology. The purpose of the study was to demonstrate the utility of thermal induction to destroy cancer cells...
What other disease affect individuals with olive pollen allergies?
Sabour Alaoui et al., found that 30.25% of the people surveyed in Béni Mellal, Morocco have a olive pollen allergy, this is within range of the prevalence found in urban (57.02%) and rural (42.98%) Morocco. It can be suggested that ...
The Immune Function of Osteoclasts
Osteoclasts (OCLs) are multi-nucleated phagocytes of monocytic origin that are responsible for bone resorption. Changes in their bone resorption function are associated with various pathologies such as osteoporosis, chronic inflammation and cancer. Intensive studies investigating the regulation of OCLs...
TAK-003 induces functional DENV cross-reactive cellular immmunity
A study by Waickman et al., aimed to investigate T cell responses induced by TAK-003. They showed that TAK-003 induces strong CD8 T cells (IFN-γ+CD107+) responses that last for at least 120 days. Induced cellular immunity was reactive to the entire DENV proteome...
Wild is better: in-bred mice born to wild mice resemble human responses
Low microbial diversity of laboratory (lab)-mice is suggested to be one of the main contributors to the discrepancy between lab-mice and humans. Rosshart et al., thus developed a wildling mouse model that genetically resembles laboratory mice...
Do NK cells play an important role in anti-Trypanosomiasis immunity?
Trypanosomiasis poses a serious threat to the agricultural economy. Treatment of the disease has severe side effects and currently no vaccine exists. Onyilagha et al., aimed to determine if NK cells play an important role during acute Trypanosomiasis.
Are MAIT cells detectable in lymph?
It is unclear whether depletion of MAIT cells in the blood is due to apoptosis or migration to sites of infection, and whether MAIT cells in blood and tissue have distinct phenotypic and functional characteristics. Voillet et al., aimed to contribute to this knowledge gap by determining if MAIT cells...
Does S. mansoni treatment affect HIV susceptibility?
Yegorov et al., employed ex vivo HIV entry assays in combination with flow cytometry, cytokine measurements and transcriptome analysis to gain insight on how standard praziquantel schistosomiasis therapy affects systemic and genital immunology of Ugandan women.