M.tb resistors: M.tb uninfected or atypical IFN-𝛾-independent M.tb immune responses ?

Lu et al., demonstrate that resistors possess a distinct adaptive immune phenotype illustrated by detection of mature Ab responses and CD40L expressing (IFN-𝛾 -ve) T cells reactive to...
May 30, 2019
Read

Course Highlight: 5th Vaccinology in Course

Very few medical interventions compete with vaccines for their cumulative impact on global health. For this reason, the Jenner institute, University of Oxford and Pirbright started vaccinology courses in Africa, where global burden of vaccine preventable...
May 24, 2019
Read

Immunoinformatics Mexico 2019: Immunologic plasticity, defense lines.

"To maintain our homeostasis we need to constantly change and adapt to the environment," said Mariana Martínez Sánchez, during her presentation titled “Plasticity in the Immune System: From Model to Mechanisms” at Immunoinformatics 2019.
May 22, 2019
Read

Immunoinformatics Mexico 2019: Part Two

Debora de Oliveira-Lopes explained the work-flow she utilises to identify epitopes for candidate for potential Schistosoma vaccines.  She begins this process by selecting immunodominant epitopes that were identified by in-vitro antibodies (Ab) selection. She then reverse transcribes the amino-acid...
May 20, 2019
Read

Immunoinformatics Mexico 2019: Part One

We shall share highlights of the first Latin-American Immuno-Informatics Course over the next series of articles. This course was attended with 36 participants and faculties from Africa and North & South America. To prepare regional scientists for the interdisciplinary Next Generation of  Immunology,
May 14, 2019
Read

Aiding Tuberculosis vaccine studies with the use of a mycobacterial growth inhibition assay

One of the major barriers to Tuberculosis vaccine development has been the lack of a correlate of protection or biomarker that can aid in the selection of vaccine candidates at early stages  of the vaccine pipeline.
May 10, 2019
Read

Further Support of the Emerging “Immunologic” Hypothesis in Mood and Eating Disorders

The brain and the immune system can communicate with each other in a few different ways. One way is through neural projections of the vagal and trigeminal nerves into different structures of the brain...
May 6, 2019
Read