6th April 2018 Classical understanding of antibody functions state that IgG and IgA antibodies confer protective systemic and mucosal immunity, respectively.
2018
Improved T cell detection by Peptide-MHC dodecamers compared to tetramers
5th April 2018 T cells via the T cell receptor (TCR) recognise peptides (antigens) presented by major histocompability complex ...
Not all RV144 vaccine induced IgA responses are bad.
28th March 2018 The RV144 or Thai Trial conducted in Thailand, is the only HIV vaccine trial to date that has demonstrated modest ...
Profiling MAITs during Multiple Myeloma
26th March 2018 Classical CD4 and CD8 T cell immunity have been the primary focus of understanding T cell immunity during cancer immunotherapy. Unlike classical T cells, unconventional cells are restricted to
How does anti-TNF treatment affect TB granuloma formation?
23rd March 2018 Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a significant problem, annually causing 1.7 million deaths worldwide. Although a significant proportion of the world population is estimated....
Immunoregulatory effects of Vitamin B5 during M.tb infection
19th March 2018 There is limited knowledge about the about the immunoregulatory effect of Vitamin B5, pantothenic acid, on the innate and adaptive immunity. Unlike Vitamin B5, vitamins A, C ...
Oral vs intradermal BCG, what’s the difference?
16th March 2018 Bacillus Calmette-Guerin (BCG) vaccine was developed in 1921 to protect individuals from developing Tuberculosis (TB) and was initially administered orally.
Which cells contribute to immunity against vaginal Zika infection ?
15th March 2018 Knowledge of Zika virus (ZIKV) immunity in the genital tract is limited. Researchers from Washington University in USA aimed to determine if subcutaneous ZIKV infection protects against ....
Can CXCL4 contribute to autoimmune pathology?
12th March 2018 Emerging research has shown increased levels of CXCL4, previously known as platelet factor 4, in various forms of T helper 17 (Th17) T cell associated rheumatic diseases. However, the exact role of CXCL4 ...
5GFTB Highlights: Human TB Challenge, is this possible?
9th March 2018 Eric Rubin from the Harvard T.H. Chan School of Public Health, is in the process of developing M.tb strains for human M.tb challenge models for TB vaccine studies. A similar challenge model is used for Malaria vaccine ...