24th July 2018 This study demonstrated the interplay between viral replicative, immunological and epidemiological
2018
How do tuft cells induce Type 2 Responses?
20th July 2018 A study conduted by Nadjsombati et al., aimed to determine how tuft cells are activated in the small intestines.Transcriptional profiling revealed that the ..
CD32: marker of HIV reservoir?
17th July 2018 A study published by Descours et al., in Nature last year, identified CD32a as marker of the CD4 T cell HIV reservoir. This study showed that CD32a+ CD4 T cells are enriched in HIV DNA ...
New Hope for TB Vaccines
13th July 2018 Tuberculosis (TB) is the leading cause of death due to infectious diseases worldwide. One of the approaches to end the TB epidemic is the development of efficacious vaccines against ...
HIV vaccine induces similar responses in humans and rhesus macaques.
10th July 2018 One of the major challenges of developing a vaccine against HIV, is the extensive HIV strain diversity. One approach being ...
Ontogeny of MAITs
6th July 2018 Researchers from France, aimed to determine the postnatal expansion and maturation of MAITs from birth to adulthood using cross-sectional samples. Ben Youssef et al., predominantly defined MAITs as Vα7.2+ CD161high T cells, as the MR1-tetarmer ...
Public Antibody Clonotypes observed in HIV+ individuals.
3rd July 2018 A collaborative research project between researchers in South Africa and US, examined the antibody repertoire in HIV ...
Another use for BCG, potential Diabetes cure?
29th June 2018 Researchers conducted a phase 1 clinical trial where individuals were either vaccinated with two doses of BCG or placebo two weeks apart, followed by the standard of care type 1 diabetes treatment.
Can testosterone regulate B cell numbers?
28th June 2018 Sex steroids are known to have great effects on the immune system. Females are known to induce stronger immune responses to vaccination than males. Furthermore, Studies have shown that the prevalence of autoimmune disorders such as ...
Initial Immune Responses to TB in the Human Lung
26th June 2018 Early immune responses to pathogens in the lungs play a role in the clearance or establishment of an infection. Our understanding of immunity in the human lung has increased over time but is still limited ...