The Infectious Diseases in Africa Symposium is taking place from the 12-16th November 2018. Immunopaedia is assiting with providing immunology content and training. We are also taking interesting interviews of the faculty.
2018
Intestinal helminth co-infection promotes control against lung migrating parasites
9th November 2018 Filbey et al., aimed to determine how chronic Heligmosomoides polygyrus (Hp) gastrointestinal infection can influence systemic and localised immunity against other helminth infections.
Characterisation of porcine conventional DC subsets
6th November 2018 DEC205 plays a very important role in antigen presentation and cross-presentation by cDCs. This has led to the study of antigen-targeting of DEC205 for vaccination.
Where do uterine NK cells during pregnancy come from?
3rd November 2018 Sojka et al., used a novel NK cell reporter mouse model to determine which cell population cNK or trNK cells is responsible for proliferation of uNK cells during pregnancy. Using this ...
Understanding follicular CD8 T cells during SIV infection
30th October 2018 Ferrando-Martinez et al., showed that SIV-specific follicular (f)CD8 T cells are observed in both intact and disorganised lymph node follicles, and accumulate during chronic infection.
Are alveolar macrophages M1 or M2 polarised?
26th October 2018 Collaboration between researchers from the United Kingdom and Malawi, aimed to investigate the polarisation of AMs detected in bronchoalveolar lavage (BAL). Studies have shown that live...
Identifying disease-associated populations in the age of big data
23rd October 2018 Researchers aimed to identify RA disease-associated cell subsets using high dimensional single cell analysis. Previous studies have observed increased proportions of CD28-CD4+ T cells in...
IgD: the lesser known antibody
17th October 2018 Unlike immunoglobulin (Ig) M, IgG, IgA and IgE, the role of IgD in antibody mediated immunity is unknown. IgD is co-expressed with IgM on mature B cells, and is best known for its function as a B cell antigen receptor. Upon antigen exposure ...
MAIT cell dysfunction during primary sclerosing cholangitis
15th October 2018 Seth and colleagues aimed to characterise the phenotype and function of MAIT cells in samples from patients with PSC. Researchers defined MAIT cells as CD161+Vα7.2 T cells that were either ...
How does bacterial-viral co-infection impact anti-viral immunity?
10th October 2018 To shed light on how bacterial infection affects LCMV induced immunity, researchers infected mice with E.coli a day post LCMV infection. Straub et al., showed that E.coli ...