29th December, 2017 CD4 T cells, particularly those capable of producing IFN-γ have been shown to play an essential role in immunity...
December 2017
Kai 1 and Kai 2, new Dog Erythrocyte Antigens: implications for clinical practice
27th December, 2017 Sensitising dogs with canine allogenic blood has enabled the identification of Dog Erythrocyte Antigens (DEA), which are clinically important regarding blood transfusion....
Expression of CD40L by CD8 T cells promotes autologous activation and differentiation
22nd December, 2017 CD40L plays an essential role during DC licensing – T cell mediated activation of Dendritic Cells (DC) and monocytes -, a process required for DCs to...
Vaccine induced T cell immunity, antigen localisation in bacterial vector matters
20th December, 2017 Attenuated bacterial vaccines are able to induce protective immunity against diseases. There has been interest in using Recombinant attenuated..
Functional antibody immunity 40 years post Ebolavirus exposure
15th December, 2017 Ebola virus diseases is caused by Ebolavirus spp, of which the Ebolavirus Zaire (EBOV-Zaire) is the most virulent and responsible for numerous Ebola outbreaks....
Immunomodulatory effect of lactic acid on the female reproductive tract
13th December, 2017 The female reproductive tract (FRT) has numerous physiological and immunological barriers against HIV infection. In addition to being a physical barrier..
Elevated Th17 cells in “healthy” overweight children
11th December, 2017 Schindler et al. demonstrated an elevated Th17 cell function in overweight children in the absence of chronic inflammatory disease or infection....
Transphagocytic CD4+ T cells are true APC capable of inducing functional CD8 memory cells
8th December, 2017 Cruz-Adalia et al. demonstrated that tpCD4 T cells are capable of priming naïve CD8 T cells, that have a predominantly...
Potential serological test capable of distinguishing Zika from Dengue infections
6th December, 2017 Antibodies play an integral role in immunity against flavivirus infection and disease, making them ideal targets for serological diagnosis of flavivirus infections.
RTS,S/AS01E induces robust central memory responses to HBsAg but not to CSP
4th December, 2017 Moncunill et al. demonstrated that RST,S/AS01E is capable of inducing CD4+ CSP- and HBsAg-specific memory cells in vaccinated children.