30th October, 2017Zika virus (ZIKV) causes major complications to fetal development and therefore a ZIKV vaccine has become one of the main focuses of research groups around the world. Researchers have isolated three...
October 2017
Antibody-drug dual combination to fight cancer
27th October, 2017Antibody-drug conjugates (ADCs) are therapeutics which combine drugs with highly antigen-specific antibodies. Currently, most of these conjugates are joined together...
Block-and-lock strategy to cure HIV
25th October, 2017Currently, there is only one known person who has been cured of HIV. New strategies must be implemented to develop an affordable, accessible cure for the virus. Researchers have identified a Tat-inhibiting drug Didehydro-Cortistatin A (dCA)...
Memory responses are not restricted to immune cells
23rd October, 2017Epithelial stem cells (EpSCs) are cells responsible for the maintenance of the epidermis of the skin by developing into skin-cell lineages to repair wounds and replace damaged skin cells.
Pharmacological treatment of lymphedema
20th October, 2017Lymphedema is a condition which affects the functioning of the lymphatic system resulting in swelling usually in the arms or legs. The condition has traditionally been managed through non-pharmacological therapies, however these therapies...
How effective are anti-TNF-α agents in treating sarcoidosis?
18th October, 2017Cutaneous sarcoidosis occurs in up to 30% of individuals with sarcoidosis. The use of anti-tumor necrosis factor (TNF)-α agents has not been fully assessed for...
Regulatory T cells delay clearance of malaria through CTLA-4
16th October, 2017Regulatory T cells (Tregs) are important in the control of the immune response. Anti-cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is a checkpoint protein.
Role of horsepox in smallpox vaccine
13th October, 2017Due to the widespread use of the smallpox vaccine, the disease was eradicated in 1980. The assumption was that the smallpox vaccine was derived from cowpox virus but since the 1930s it was known that the virus used in the vaccine was...
Short chain fatty acids improve inflammation of the eye
11th October, 2017Immune-mediated inflammation of the uvea is one of the major causes of uveitis. Recent studies have linked intestinal microbiomes and their metabolites to...
Probiotics induce double-positive intraepithelial lymphocytes
9th October, 2017Oral tolerance is important in ensuring that the body does not mount an immune response against everyday foods we ingest. CD4+CD8αα+ double-positive intraepithelial lymphocytes (DP IELs)...