IL-4–producing B cells shift T cells to Th2 responses

29th September, 2017T helper (Th) 2 cells have been shown to be important in protection against Schistosoma mansoni while increasing susceptibility to Leishmania major. Researchers...
September 29, 2017
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Type I interferons are important in anti-helminth Th2 immunity

27th September, 2017Type I interferons (IFN) have been traditionally associated with innate immune defences against viruses and bacteria which ultimately result in Th1/17-type...
September 27, 2017
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Trispecific antibody for HIV therapy

22nd September, 2017One avenue that is being explored in a HIV vaccine is eliciting neutralising antibody responses. However, the diversity of the virus has made this challenging. Researchers from the National Institute of Allergy and Infectious Diseases...
September 22, 2017
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Antibodies protect against cytomegalovirus infection

20th September, 2017Human cytomegalovirus (HCMV) is a cause of major concern as it causes severe disease in immunocompromised individuals. Therefore, a vaccine to prevent the virus...
September 20, 2017
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Investigating HIV RNA expression during antiretroviral therapy

18th September, 2017Although antiretroviral therapy (ART) can suppress most HIV replication, the virus establishes reservoirs and these cells may undergo proliferation despite the treatment.
September 18, 2017
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Gut bacteria induce pro-inflammatory response in MS

15th September, 2017Multiple Sclerosis (MS) is a condition which affects the central nervous system. Researchers from Stanford University School of Medicine have now found a link...
September 15, 2017
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Severity of leishmania infection depends on time of day

13th September, 2017The Leishmania parasite mostly invades neutrophils and macrophages to establish infection. These innate immune cells have internal circadian clocks which...
September 13, 2017
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Multi-site injections enhance immune responses

11th September, 2017Several approaches to enhance immunity against tumor cells in cancer patients have been proposed. Therapeutic vaccination has been reported to be one of the most...
September 11, 2017
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Histamine releasing factor makes host vulnerable to malaria

6th September, 2017Malaria has remained major health problem in many developing countries especially sub-Saharan Africa. This has led to the search of an effective vaccine in order...
September 6, 2017
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Plasmodium infection promotes bone loss

4th September, 2017Malaria disease is the result of infection with Plasmodium parasites.  The infection is known to cause some long term adverse effects after the clearance of the parasite including bone loss.
September 4, 2017
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