Allergy and asthma across generations

A recent review evaluated current findings on multigenerational studies of allergy and asthma, where atypical immunological traits may be passed down generations through epigenetics. Multigenerational cohorts where subjects are observed starting from pregnancy...
May 31, 2017
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Microbiota in T cell survival

Commensal microbiota found in humans has been found to impact various autoimmune diseases by a link to T cell development. The mechanisms behind this were not well understood. Researchers at the University of Utah School of Medicine, have now...
May 29, 2017
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Early Introduction of Peanuts Prevents Allergies

While many people believe that peanut allergies are confined to Western countries, this growing problem has actually spread to Africa and Asia. The prevalence of peanut allergies in North America...
May 26, 2017
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MyD88-mediated cells against C. rodentium identified

Citrobacter rodentium-induced inflammation is a commonly used animal model for enterohemorragic Escherichia coli (EHEC) infection. It is known that C. rodentium infection is an...
May 24, 2017
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Cross-reactive antibodies for Ebola vaccine

With the recent Ebola cases identified in the Democratic Republic of Congo, the need for a protective vaccine to prevent and control future outbreaks is once again highlighted. Researchers from...
May 21, 2017
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Engineered CD8 T cells flush out HIV reservoirs

When CD4 T cells are infected with HIV, CD8 cytotoxic T cells usually move in to kill the infected cells. However, some CD4...
May 19, 2017
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Targeting an integrin as a potential HIV therapeutic

α4β7 is a gut-homing integrin which is another receptor used by HIV to enter cells. For this reason, it plays a critical role in the pathogenesis of the virus.
May 17, 2017
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Marginal zone B cells in cholesterol control

B cells play an important role in the immune response towards lipoproteins involved in atherosclerosis. Scientists have now discovered a previously unknown role for splenic marginal zone B...
May 14, 2017
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HIV immunogen based on precursor antibodies

More than 30 years after the discovery that HIV is the cause of AIDS, there is still no vaccine for this virus. One of the challenges...
May 12, 2017
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MHC Ib molecule protects against TB infection

Tuberculosis is one of the most dangerous infectious diseases with high morbidity and mortality especially in southern Africa. In this region, TB-HIV...
May 9, 2017
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