Nov 23rd, 2015
During HIV infection, cytotoxic T lymphocytes (CTL) are able to eliminate virally infected cells at the acute stage of infection.
2015
Microbial Gut diversity predicts immune status during HIV-1 infection
Nov 20th, 2015
It is known that HIV-1 infection alters intestinal barrier, causes gut microbiota dysbiosis, and results in systemic inflammation.
Stasis of CD8+ T Cells in the brain is a Signature of Cerebral Malaria
Nov 18th, 2015
In the November 12th edition of PloS Pathogens, Shaw et al explored the role of CD8+ T cells in an experimental model of cerebral malaria
Diversity of lipid envelopes in Mycobacterium tuberculosis
Nov 17th, 2015
Multi-drug resistant forms of Mycobacterium tuberculosis (M.tb) hamper global efforts to control the spread of TB, a threat to public health
A new reservoir of HIV found within peripheral Vδ2 T cells
Nov 13th, 2015
Conventional T cells (which have an alpha:beta T cell receptor) make up the majority of T cells in the peripheral circulation....
A new marker denotes exhausted CD8+ T cells during chronic viral infections
Nov 11th, 2015
Persistent viruses induce a state of chronic viral infection that is characterized by inducing a state of T cell........
New antibodies that target sugars on the HIV-1 envelope
Nov 9th, 2015
The CD4 binding site on the gp120 portion of the envelope protein of HIV-1 is a vulnerable site, that when targeted could cripple ...
Nucleoside reverse-transcriptase inhibitors (NRTIs) as first-line ART in African Children
Oct 9th, 2015
There have been no paediatric trials which have compared nucleoside reverse-transcriptase..
What causes the high mutation rates of HIV-1 in the human body?
Oct 7th, 2015
It has been known for a long time that HIV-1 mutates rapidy, and does so to escape the pressure
Is Adipose Tissue a viral reservoir?
Oct 5th, 2015
Adipose tissue is made up of adipocytes and the stromal vascular fraction (SVF), which comprises immune cells such as CD4+ T cells....