Based on previous research it has been suggested that protease inhibitors might produce...
2014
Viral reservoirs limited by ART
A study on viral reservoirs in rhesus macaque monkey...
The role of Cas1 and 2 proteins and immunity
Bacteria are under constant attack from foreign genetic elements...
T. gondii ligand shown to promote inflammatory monocytes and provide resistance to bacterial infection
Previous murine studies have shown that mice with a chronic Toxoplasma gondii infection ...
Characterization of pandemic influenza immune memory after vaccination or infection
Influenza A infection is still a major infectious disease that has appreciable morbidity and mortality as evidenced during the pandemic in 2009. Furthermore antibody responses acquired after natural infection or seasonal vaccination do not confer long-time protection against all strains because of the high …
First-line boosted protease inhibitor regimen remains effective after virologic failure
Boosted protease inhibitor and nucleoside reverse transcriptase inhibitors (NRTIs) is a regimen that is often used as a first line treatment regimen as it has the advantage of rarely resulting in the emergence of resistant virus should virologic failure occur. Although the best approach …
ART in acute infection limits viral reservoirs
This study from the vaccine and gene therapy institute in Florida looked at the effect of early treatment on viral reservoirs in rhesus macaque monkeys infected with SIV, a primate virus similar to HIV, when antiretroviral therapy (ART) is started either prior to peak …
Kaposi Sarcoma treated with pegylated interferon
Kaposi Sarcoma (KS) is the most common AIDS-defining cance...
Broad-spectrum anti-biofilm peptide targets cellular stress response
Bacteria colonise environments by forming biofilms, which are extremely resistant to conventional antibiotics. For this reason biofilms are the cause of many infections, particularly where there are device-related infections, infections on body surfaces and in chronic infections. Currently, many known antibiotics are losing their …
HIV sexual transmission risk among serodiscordant couples
A mathematical model of the current knowledge about the efficacy...