The chemokine CXCL12 and its cognate receptor CXCR4 perform multiple functions...
February 2014
Agonistic induction of PPARy shown to reverse emphysema
Cigarette smoke is the most common cause of pulmonary emphysema, which results in an irreversible loss of lung structure and function. Lung myeloid dendritic cells (mDCs) derived from cigarette smokers activate autoreactive Th1 and Th17 immune responses and thus have been implicated in emphysema …
Treating rhematoid arthritis with peptide-specific CD8+ regulatory T cells
The autoimmune disorder rheumatoid arthritis (RA) is characterized by joint inflammatio...
Tolerance or resistance to HIV infection? Which is it?
Tolerance in biology can have different meanings, depending on context...
UTI treatment requires a coordinated phagocytic response
Urinary tract infections (UTIs) require the innate immune system to control and clear the bacteria...
Memory regulatory T cells reside in human skin
It was originally thought that regulatory T cells (Tregs) which are characterized by...
T cell repertoire following autologous stem cell transplantation for multiple sclerosis
Autologous haematopoietic stem cell transplantation (HSCT) is typically used in haematologic ...